Systems Biology Questions in Cell Polarity

A full-time postdoctoral position is available in the Altschuler & Wu Laboratory, Division of Systems Biology, Green Comprehensive Center for Molecular, Computational, and Systems Biology and the Department of Pharmacology at the University of Texas Southwestern Medical Center.

The successful candidate will investigate design principles underlying cell polarization.  Our lab investigates mechanisms of spatial and temporal organization using a combined approach of mathematical modeling, molecular biology, and quantitative microscopy (http://hhmi.swmed.edu/Labs/ms/ ).

Applicants should have a Ph.D. in either biological or mathematical sciences. Applicants with a Ph.D. in biological sciences should have a strong background in standard molecular biology techniques and microscopy with interest in investigating and working with quantitative measurement of network behaviors combined with mathematical modeling.   Applicants with a Ph.D. in mathematical sciences should have a strong background in mathematical analysis, signal processing or scientific programming with interests in investigating biological questions and working with biological systems.

Applicants should submit a brief one-page description of research interests and plans, a resume, and contact information for three references to Dr. Lani Wu via e-mail.

UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer

Systems Biology Questions in Glucose Homeostasis

A full-time postdoctoral position is available in the Altschuler & Wu laboratory, Division of Systems Biology, Green Comprehensive Center for Molecular, Computational, and Systems Biology and the Department of Pharmacology at the University of Texas Southwestern Medical Center.

The successful candidate will investigate mechanisms underlying glucose homeostasis.  Our approaches combine biochemistry, molecular and cell biological studies with fluorescence microscopy and mathematical analysis (http://hhmi.swmed.edu/Labs/ms/ ).

Applicants should have a Ph.D. in biological sciences with strong background in biochemistry, molecular or cell biology.  Previous experience in pancreatic islet biology, insulin signaling, metabolism, fluorescence imaging and primary cell culture are highly desirable.

Applicants should submit a brief one-page description of research interests and plans, a resume, and contact information for three references to Dr. Lani Wu via e-mail.

UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer

Signal Processing

A full-time postdoctoral position is available in the Altschuler & Wu laboratory, Division of System Biology, Green Comprehensive Center for Molecular, Computational, and Systems Biology and the Department of Pharmacology at the University of Texas Southwestern Medical Center. The successful candidate will develop new automated algorithms for analyzing high content microscopy images with the aim to study reactions of cells under different perturbations. The focus of the lab is to combine modeling and experiments to investigate mechanisms underlying properties of spatial and temporal organization of cells (http://hhmi.swmed.edu/Labs/ms/). The lab is highly multi disciplinary and the successful candidate will have the opportunity to work side-by-side with biologists on the bench.

Applicants should have (or be about to receive) a Ph.D. in Electrical or Computer Engineering, Computer Science, Statistics, Applied Mathematics, or other closely related fields. A strong background in image/signal processing, probability theory, pattern recognition, bioinformatics, and scientific programming is required. Previous experience in analyzing high dimensional biological data (such as those generated from fluorescent microscopy, DNA microarray, or mass spectrometry) is highly desirable.

Applicants should submit a brief one-page description of research interests and plans, a resume, and contact information for three references to Dr. Altschuler via e-mail (Steven.Altschuler@UTSouthwestern.edu).

UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer