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Research News — September 2008
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  Dr. Roger Unger new low res  
 
Dr. Roger Unger
 
 
 
     
Location of body fat predicts risk
for disease better than weight
Scientists at UT Southwestern have found a potential new way to stop the bacteria that cause gastroenteritis, tularemia and severe diarrhea from making people sick. The researchers found that the molecule LED209 interferes with the biochemical signals that cause bacteria in our bodies to release toxins. “Most people today think that obesity itself causes metabolic syndrome,” said Dr. Roger Unger, professor of internal medicine at UT Southwestern and senior author of the study. Read More

Older corneas remain suitable for transplantion
Surgeons and patients from
UT Southwestern and
UT Southwestern Transplant Services Center joined in a landmark study showing that corneas from older donors are as successful for transplants after five years as is tissue from younger donors, allowing possible expansion of the donor pool. Read More

Molecular 'clock' could reveal risk of breast cancer
A chemical reaction in genes that control breast cancer provides a molecular clock that could one day help researchers more accurately determine a woman’s risk for developing breast cancer and provide a new approach for treatment, UT Southwestern researchers have found. Read More

Digestive specialists use freezing to prevent esophageal cancer
UT Southwestern gastroenterologists are using a new method to freeze damaged cells in the esophagus, preventing them from turning cancerous. Read More

Protein thought to promote cancer instead functions as tumor-suppressor

A protein previously thought to promote colorectal cancer instead suppresses the growth of human cancer cells in culture, researchers at UT Southwestern have found. Read More

Molecule prompts stem cells to repair heart damage
Inspired by a chance discovery during another experiment, researchers at
UT Southwestern have created a small molecule that stimulates nerve stem cells to begin maturing into nerve cells in culture. Read More

STAR*D research team tests two-drug approach
Hoping to answer a question raised by the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study, UT Southwestern researchers have designed the Combining Medication to Enhance Outcomes of Depression (CO-MED) trial to test multiple-medication treatment of depression. Read More

Gene shift in mice mimics sleep disorder
Mutations in two genes that control electrical excitability in a portion of the brain involved in sleep create a human-like insomnia disorder in mice. Read More

New model predicts how cancer patients will fare after 12 years of treatment
A UT Southwestern physician and other researchers have developed a unique statistical model that predicts the probability of a patient being cancer free 12 years after initial surgical treatment. Read More

Starvation-linked hormone could lead to longer life span
Researchers at UT Southwestern have determined that starvation blocks the effects of growth hormone via a mechanism that may have implications in treating diabetes and extending life span. Read More

Nanotechnology, biomolecules, light unite to 'cook' cancer cells
Researchers are testing a new way to kill cancer cells selectively by attaching cancer-seeking antibodies to tiny carbon tubes that heat up when exposed to near-infrared light. Read More

Scientists discover attack mechanism of bacterium found in shellfish
An infectious ocean-dwelling bacterium found in oysters and other shellfish kills its host’s cells by causing them to burst, providing the invader with a nutrient-rich meal, researchers at UT Southwestern have found. Read More