Currently, we have several clinical trials in progress.  Please contact our Clinical Research Coordinator, Mary Delira, RN, BSN, at 214-645-7728 for information about current and upcoming clinical trials in cardiothoracic surgery.

Current clinical trials:

• Management of excessive bleeding following cardiopulmonary bypass:  A pilot feasibility study
• Chronic Rejection Study:  Lung Transplant
• The effects of Nitric Oxide for inhalation during Left Ventricular Assist Device (LVAD) implantation
• Interagency registry of mechanically assisted circulatory support
• Multi-Center study to evaluate the cardioprotective effects of MC-1 in patients undergoing high-risk coronary artery bypass graft (CABG) surgery
• Thymectomy for patients with myasthenia gravis - a 10 year surgical analysis
• Clinical trial of the On-X valve using low dose anticoagulation
• Mitral valve surgery study

The following are selected closed clinical trials that provide an example of the studies in our department.  Please select from the following to obtain more information.

• Utilization of an epidermal growth factor Receptor Antagonist, ZD 1839 (IRESSA), in completely resected primary stage IB, II, and IIIA Non-Small Cell Lung Cancer (NSCLC)  
• The evaluation of nesiritide infusion, initiate post induction of anesthesia, in the management of Coronary Artery Bypass Graft (CABG) patients requiring cardiopulmonary bypass (CPB)
• The evaluation of PEN110-treated RBCs in surgical patients
• A study to determine the safety and effectiveness of REPEL-CV for reducing post-operative adhesions following pediatric cardiothoracic surgery
• Surgical Treatment for Ischemic Heart (STICH)
• The effects of Nitrous Oxide (NO) for inhalation during left ventricular assist device (LVAD) implantation
• Ex-Vivo Treatment with CGT003 of Coronary Vein Grafts in Patients Undergoing Coronary Artery Bypass Graft (CABG) procedures
• Catheter-based therapy of pleural effusions in cancer patients (optimal pleural effusion control, OPEC) CALGB #30102