The following list details the publications by faculty members of the Department of Radiation Oncology at The University of Texas Southwestern Medical Center at Dallas. The listings are comprised of articles published in peer reviewed journals and books, as well as non-peer reviewed articles (reviews, book chapters).
Yijima H, Lee KJ, Chen BP. ATR-dependent DNA-PKcs phosphorylation in response to UV-induced replication stress. Mol Cell Biol. 26:7520-8, 2006.
Das AK, Sato M, Story MD, Peyton M, Graves R, Redpath R, Girard L, Gazdar AF, Shay JW, Minna JD, Nirodi CS. Non-small cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation. Cancer Res. 66:9601-8, 2006.
Nguyen NP, Frank C, Moltz CC, Vos P, Smith HJ, Bhamidipati PV, Karlsson U, Nguyen PD, Alfieri A, Nguyen LM, Lemanski C, Chan W, Rose S, Sallah S. Aspiration rate following chemoradiation for head and neck cancer: An underreported occurrence. Radiother Oncol. 80(3):302-6, 2006.
Lo SS, Abdulrahman R, Desrosiers PM, Fakiris AJ, Witt TC, Worth RM, Dittmer PH, Desrosiers CM, Frost S, Timmerman RD. The role of Gamma Knife Radiosurgery in the management of unresectable gross disease or gross residual disease after surgery in ependymoma. J Neurooncol. 79(1):51-6, 2006.
Burma S, Chen BP, Chen DJ. Role of non-homologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair. 5:1042-8, 2006.
Silvera D, Koloteva-Levine N, Burma S, Elroy-Stein O. Effect of Ku proteins on IRES-mediated translation. Biol Cell. 98(6):353-61, 2006.
Teh BS, Bastasch MD, Mai WY, Kattan MW, Butler EB, Kadmon D. Long-term benefits of elective radiotherapy after prostatectomy for patients with positive surgical margins. J Urol. Jun;175(6):2097-101; discussion 2101-2, 2006.
Nguyen NP, Moltz CC, Frank C, Karlsson U, Nguyen PD, Vos P, Smith HJ, Dutta S, Nguyen LM, Lemanski C, Chan W, Sallah S. Dysphagia severity following chemoradiation and postoperative radiation for head and neck cancer. Eur J Radiol. 59(3):453-9, 2006.
Lotan Y, Stanfield J, Cho LC, Sherwood JB, Abdel-Aziz KF, Chang CH, Forster K, Kabbani W, Hsieh JT, Choy H, Timmerman R. Efficacy of high dose per fraction radiation for implanted human prostate cancer in a nude mouse model. J Urol. 175(5):1932-6, 2006.
Mukherjee B, Kessinger C, Kobayashi J, Chen BP, Chen DJ, Chatterjee A, Burma S. DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells.
DNA Repair. 10;5(5):575-90, 2006.
Yang F, Stenoien DL, Strittmatter EF, Wang J, Ding L, Lipton MS, Monroe ME, Nicora CD, Gristenko MA, Tang K, Fang R, Adkins JN, Camp DG 2nd, Chen DJ, Smith RD. Phosphoproteome profiling of human skin fibroblast cells in response to low- and high-dose irradiation. J Proteome Res. 5(5):1252-60, 2006.
Perry JJ, Yannone SM, Holden LG, Hitomi C, Asaithamby A, Han S, Cooper PK, Chen DJ, Tainer JA. WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat Struct Mol Biol. 13(5):414-22, 2006.
Kavanagh BD, McGarry RC, Timmerman RD. Extracranial radiosurgery (stereotactic body radiation therapy) for oligometastases. Semin Radiat Oncol. 16(2):77-84, 2006.
Walsh L, Stanfield JL, Cho LC, Chang CH, Forster K, Kabbani W, Cadeddu JA, Hsieh JT, Choy H, Timmerman R, Lotan Y. Efficacy of Ablative High-Dose-per-Fraction Radiation for Implanted Human Renal Cell Cancer in a Nude Mouse Model. Eur Urol. 50(4):795-800; discussion 800, 2006.
Giri U, Ashorn CL, Ramdas L, Stivers DN, Coombes K, El-Naggar AK, Ang KK, Story MD. Molecular signatures associated with clinical outcome in patients with high-risk head-and-neck squamous cell carcinoma treated by surgery and radiation. Int J Radiat Oncol Biol Phys. Mar 1;64(3):670-7, 2006.
Mukhopadhyay P, Ali MA, Nandi A, Carreon P, Choy H, Saha D. The cyclin-dependent kinase 2 inhibitor down-regulates interleukin-1beta-mediated induction of cyclooxygenase-2 expression in human lung carcinoma cells. Cancer Res. 66(3):1758-66, 2006.
Kavanagh BD, Timmerman RD. Stereotactic radiosurgery and stereotactic body radiation therapy: an overview of technical considerations and clinical applications. Hematol Oncol Clin North Am. 20(1):87-95, 2006.
Bastasch MD, Teh BS, Mai WY, McGary JE, Grant WH 3rd, Butler EB. Tolerance of endorectal balloon in 396 patients treated with intensity-modulated radiation therapy (IMRT) for prostate cancer. Am J Clin Oncol. 29(1):8-11, 2006.
Kapur P, Rakheja D, Bastasch M, Molberg KH, Sarode VR. Primary mucinous adenocarcinoma of the thymus: a case report and review of the literature. Arch Pathol Lab Med. 130(2):201-4, 2006.
Timmerman RD, Story M. Stereotactic body radiation therapy: a treatment in need of basic biological research. Cancer J. 12(1):19-20, 2006.
Dynlacht JR, Tyree C, Valluri S, DesRosiers C, Caperell-Grant A, Mendonca MS, Timmerman R, Bigsby RM. Effect of estrogen on radiation-induced cataractogenesis. Radiat Res. 165(1):9-15, 2006.
Henderson MA, Valluri S, Lo SS, Witt TC, Worth RM, Danis RP, Timmerman RD. Gamma Knife Radiosurgery in the Treatment of Choroidal Neovascularization (Wet-Type Macular Degeneration). Stereotact Funct Neurosurg. 85(1):11-17, 2006.
Timmerman R, McGarry R, Yiannoutsos C, Papiez L, Tudor K, DeLuca J, Ewing M, Abdulrahman R, DesRosiers C, Williams M, Fletcher J. Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer. J Clin Oncol. 24(30):4833-9, 2006.
Kavanagh BD, Schefter TE, Cardenes HR, Stieber VW, Raben D, Timmerman RD, McCarter MD, Burri S, Nedzi LA, Sawyer TE, Gaspar LE. Interim analysis of a prospective phase I/II trial of SBRT for liver metastases. Acta Oncol. 45(7):848-55, 2006.
Timmerman R, Galvin J, Michalski J, Straube W, Ibbott G, Martin E, Abdulrahman R, Swann S, Fowler J, Choy H. Accreditation and quality assurance for Radiation Therapy Oncology Group: Multicenter clinical trials using Stereotactic Body Radiation Therapy in lung cancer. Acta Oncol. 45(7):779-86, 2006.
Henderson MA, Shirazi H, Lo SS, Mendonca MS, Fakiris AJ, Witt TC, Worth RM, Timmerman RD. Stereotactic radiosurgery and fractionated stereotactic radiotherapy in the treatment of uveal melanoma. Technol Cancer Res Treat. 5(4):411-9, 2006.
Non-Peer Reviewed Articles (Reviews, Books, Book Chapters)
Burma S, Chen BP, Chen DJ. 2006. Chapter 6: Role of Non-homologous End Joining in Repair of DNA Double-Strand Break. Book title: DNA Repair, Genetic Instability, and Cancer.
Choy H. Satraplatin: an orally available platinum analog for the treatment of cancer. Expert Rev Anticancer Ther. 6(7):973-82, 2006. Review.
Choy H . RTOG current clinical trials in lung cancer. Overview. Clin Adv Hematol Oncol. 2005 Aug;3(8):624-5.
Choy H, Nabid A, Stea B, Scott C, Roa W, Kleinberg L, Ayoub J, Smith C, Souhami L, Hamburg S, Spanos W, Kreisman H, Boyd AP, Cagnoni PJ, Curran WJ. Phase II multicenter study of induction chemotherapy followed by concurrent efaproxiral (RSR13) and thoracic radiotherapy for patients with locally advanced non-small-cell lung cancer. J Clin Oncol. 2005 Sep 1;23(25):5918-28.
Akerley W, Herndon JE Jr, Lyss AP, Choy H, Turrisi A, Graziano S, Williams T, Zhang C, Vokes EE, Green MR. Induction paclitaxel/carboplatin followed by concurrent chemoradiation therapy for unresectable stage III non-small-cell lung cancer: a limited-access study--CALGB 9534. Clin Lung Cancer. 2005 Jul;7(1):47-53.
Belani CP, Choy H, Bonomi P, Scott C, Travis P, Haluschak J, Curran WJ Jr. Combined chemoradiotherapy regimens of paclitaxel and carboplatin for locally advanced non-small-cell lung cancer: a randomized phase II locally advanced multi-modality protocol. J Clin Oncol. 2005 Sep 1;23(25):5883-91.
Kim DW, Shyr Y, Shaktour B, Akerley W, Johnson DH, Choy H. Long term follow up and analysis of long term survivors in patients treated with paclitaxel-based concurrent chemo/radiation therapy for locally advanced non-small cell lung cancer. Lung Cancer. 2005 Nov;50(2):235-45.
Tedesco KL, Berlin J, Rothenberg M, Choy H, Wyman K, Scott Pearson A, Daniel Beauchamp R, Merchant N, Lockhart AC, Shyr Y, Caillouette C, Chakravarthy B. A phase I study of concurrent 9-nitro-20(s)-camptothecin (9NC/Orathecin) and radiation therapy in the treatment of locally advanced adenocarcinoma of the pancreas. Radiother Oncol. 2005 Jul;76(1):54-8.
Kim DW, Shyr Y, Chen H, Akerley W, Johnson DH, Choy H. Response to combined modality therapy correlates with survival in locally advanced non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2005 May 20.
Tedesco KL, Berlin J, Blanke CD, Teng M, Choy H, Roberts J, Beauchamp RD, Leach S, Wyman K, Tarpley J, Shyr Y, Caillouette C, Chakravarthy B. Phase I trial of Orzel (UFT plus leucovorin), cisplatin, and radiotherapy in the treatment of potentially resectable esophageal cancer. Int J Radiat Oncol Biol Phys. 2005 Apr 1;61(5):1364-70.
Giller CA, Berger BD, Pistenmaa DA, Sklar F, Weprin B, Shapiro K, Winick N, Mulne AF, Delp JL, Giolio JP, Gall KP, DIcke KA, Swift D, Sacco D, Harris-Henderson K, Bowers D. Robotically guided radiosurgery for children. Pediatr Blood Cancer, 2005 Sep;45(3):304-10.
Timmerman, RD, Forster, KM, Cho, LC. Extracranial Stereotactic Radiation Delivery. Seminars in Radiat Oncol 15(3):202-207, 2005.
Schefter TE, Kavanagh BD, Timmerman RD, Cardenes HR, Baron A, Gaspar LE. A phase I trial of stereotactic body radiation therapy (SBRT) for liver metastases. Int J Radiat Oncol Biol Phys. 2005 Aug 1;62(5):1371-8.
Timmerman R, Kavanagh B. Stereotactic body radiation therapy. Curr Prob Cancer. 2005 May-Jun;29(3):120-57.
Timmerman RD, Forster KM, Chinsoo Cho L. Extracranial stereotactic radiation delivery. Semin Radiat Oncol. 2005 Jul;15(3):202-7.
McGarry RC, Papiez L, Williams M, Whitford T, Timmerman RD . Stereotactic body radiation therapy of early-stage non-small-cell lung carcinoma: Phase I study. Int J Radiat Oncol Biol Phys. 2005 Aug 19
Zhu XR, Prado K, Liu HH, Guerrero TM, Jeter M, Liao Z, Rice D, Forster K, Stevens CW . Intensity-modulated radiation therapy for mesothelioma: impact of multileaf collimator leaf width and pencil beam size on planning quality and delivery efficiency. Int J Radiat Oncol Biol Phys. 2005 Aug 1;62(5):1525-34.
Timmerman RD , Forster KM, Chinsoo Cho L . Extracranial stereotactic radiation delivery. Semin Radiat Oncol. 2005 Jul;15(3):202-7.
Stevens CW, Wong PF, Rice D, Jeeter M, Forster K, Zhu XR . Treatment planning system evaluation for mesothelioma IMRT. Lung Cancer. 2005 Jul;49 Suppl 1:S75-81.
Munden RF, Erasmus JJ, Smythe WR, Madewell JE, Forster KM, Stevens CW . Radiation injury to the liver after intensity-modulated radiation therapy in patients with mesothelioma: an unusual CT appearance. AJR Am J Roentgenol. 2005 Apr;184(4):1091-5.
Sasaki R, Komaki R, Macapinlac H, Erasmus J, Allen P, Forster K, Putnam JB, Herbst RS, Moran CA, Podoloff DA, Roth JA, Cox JD . [18F]fluorodeoxyglucose uptake by positron emission tomography predicts outcome of non-small-cell lung cancer. J Clin Oncol. 2005 Feb 20;23(6):1136-43.
Guerrero T, Zhang G, Segars W, Huang TC, Bilton S, Ibbott G, Dong L, Forster K, Lin KP . Elastic image mapping for 4-D dose estimation in thoracic radiotherapy. Radiat Prot Dosimetry. 2005;115(1-4):497-502.
Beddar AS, Salehpour M, Briere TM, Hamidian H, Gillin MT . Preliminary evaluation of implantable MOSFET radiation dosimeters. Phys Med Biol. 2005 Jan 7;50(1):141-9.
Ding LH, SHingyoji M, Chen F, Hwang JJ, Burma S, Lee C, Cheng JF, Chen DJ . Gene expression profiles of normal human fibroblasts after exposure to ionizing radiation: a comparative study of low and high doses. Radiat Res. 2005 Jul:164(1):17-26.
Chen BP, Chan DW, Kobayashi J, Burma S, Asaithamby A, Morotomi-Yano K, Botvinick E, Qin J, Chen DJ . Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J Biol Chem. 2005 Apr 15;280(15):14709-15.
Al Rashid ST, Dellaire G, Cuddihy A, Jalali F, Vaid M, Coackley C, Folkard M, Xu Y, Chen BP, Chen DJ, Lilge L, Prise KM, Bazett Jones DP, Bristow RG . Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo. Cancer Res. 2005 Dec 1;65(23):10810-21.
Schwartz M, Zlotorynski E, Goldberg M, Ozeri E, Rahat A, le Sage C, Chen BP, Chen DJ, Agami R, Kerem B. Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability. Genes Dev. 2005 Nov 15;19(22):2715-26.
Giri U, Ashorn CL, Ramdas L, Stivers DN, Coombes K, Naggar AE, Ang KK, Story MD . Molecular Signatures Associated with Clinical Outcome in Patients with High-Risk Head-and-Neck Squamous Cell Carcinoma Treated by Surgery and Radiation. Int J Radiat Oncol Biol Phys. 2005 Nov 9.
Giri U, Terry NH, Kala SV, Lieberman MW, Story MD . Elimination of the differential chemoresistance between the murine B-cell lymphoma LY-ar and LY-as cell lines after arsenic (As2O3) exposure via the overexpression of gsto1 (p28). Cancer Chemother Pharmacol. 2005 Jun;55(6):511-21.
Rouzer CA , Jacobs AT, Nirodi CS, Kingsley PJ, Morrow JD, Marnett LJ . RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-alpha secretion. J Lipid Res. 2005 May;46(5):1027-37.
Non-Peer Reviewed Articles (Reviews, Books, Book Chapters)
Kavanagh, B., Timmerman, R.D., editors, Stereotactic Body Radiation Therapy, Lippincott, Williams, and Wilkins, Baltimore, MD, 2005.
Garwood DP: Testicle , In Textbook of Radiation Oncology, Leibel SA and Phillips, TL, eds, second edition W.B. Saunders Company, 2005. (update of prior chapter)
Crownover RL and Garwood DP: Extracranial Stereotactic Radioablation , In Textbook of Radiation Oncology, Leibel SA and Phillips TL, eds, second edition, W. B Saunders Company,2005.
Timmerman, R, and Lohr, F: Normal Tissue Dose Constraints Applied in Stereotactic Body Radiation Therapy, In Stereotactic Body Radiation Therapy, Chapter 4, Lippincott, Williams, and Wilkins, Baltimore, MD, 2005, pp 29-37.
Papiez, L, Moskvin, V, and Timmerman, R: Dosimetry of Stereotactic Body Radiation Therapy Treatments, In Stereotactic Body Radiation Therapy, Chapter 4, Lippincott, Williams, and Wilkins, Baltimore, MD, 2005, pp 57-68.
Timmerman, RD, Kavanagh, B: Stereotactic Body Radiation Therapy: Toward the Proper Implementation of Technical and Biological Innovation, In the 2005 ACRO Practice Management Guidelines (solicited and submitted 11/04).
Cho LC, Dowell JE, Garwood D, Spangler A, Choy H. Prophylactic cranial irradiation with combined modality therapy for patients with locally advanced non-small cell lung cancer. Semin Oncol. 2005 Jun;32(3):293-8. Review.
