The following list details the publications by faculty members of the Department of Radiation Oncology at The University of Texas Southwestern Medical Center at Dallas. The listings are comprised of articles published in peer reviewed journals and books, as well as non-peer reviewed articles (reviews, book chapters).
2008 Publications
Ken-ichi Yano, Keiko Morotomi-Yano, Shih-Ya Wang, Naoya Uematsuw, Kyung-Jong Lee, Aroumougame Asaithamby, Eric Weterings & David J. Chen, Ku recruits XLF to DNA double-strand breaks, EMBO report, 2008, 9(1), 91-96.
Dewight. R. Williams, Kyung-Jong Lee, J. Shi, David. J. Chen, Phoebe. L. Stewart, Subnanometer Resolution structure of DNA-Pkcs by Cryoelectron Microscopy Reveals Helices, Structure, 2008 16(3) 468-477 (Cover paper).
Hirohiko Yajima, Kyung-Jong Lee, Benjamin P Chen, Late phase activation of ATM in response to replication stress, J Mol Biol. Accepted
Mingan Shi, Carolyn J. Vivian, Kyung-Jong Lee, Chunmin Ge, Keiko Morotomi Yano, Claudia Manzl, Florian Bock, Shigeo Sato, Chieri Sato, Ruihong Zhu, Selene K. Swanson, Michael P. Washburn, David J. Chen, Benjamin P. C. Chen, Andreas Villunger, Laurence Florens, Chunying Du, DNA-PKcs-PIDDosome: A Nuclear Caspase-2-Activating Protein Complex Required for a G2/M DNA Damage Checkpoint and DNA Nonhomologous End-Joining (submitted)
Konstantin Akopiants, Rui-Zhe Zhou, Susovan Mohapatra, Kristoffer Valerie, Susan Lees-Miller, Kyung-Jong Lee; David Chen, Patrick Revy, de , Jean Pierre Villartay, Lawrence Povirk, Requirement for XLF/Cernunnos in alignment-based gap filling for nonhomologous DNA end joining in human whole-cell extracts. (submitted)
Kyung-Jong Lee, Junhua Wang, Hirohiko Yajima, Benjamin Chen, DNA-Pkcs sis required for metaphase-to-anaphase transition and chromosome segregation during mitosis. (Manuscript in preparation)
Choy, H. The University of Texas Health Science Center at San Antonio. “Recent Advances in the Management of Locally Advanced Non-Small Cell Lung Cancer”. San Antonio, TX 7/25/2008
C. Park, L. Papiez, S. Zhang, M. Story and R. Timmerman,“The Unifying (Hybrid) Survival Curve and Single Fraction Equivalent Dose: Useful Tools in Understanding the Potency of Ablative Radiation Therapy”, Int. J. Rad. Oncol. Biol. Phys. 70, 847–852 (2008).
L. Papiez and R. Timmerman, “Hypofractionation in radiation therapy and its impact", Med. Phys. 35, 112-118 (2008).
L. Papiez and R. M. Abolfath, “Variable beam dose rate and DMLC IMRT to moving body anatomy”, Med. Phys. (submitted).
R. McMahon, L. Papiez, R. Berbeco, S. Nishioka and H. Shirato “An improved MLC control algorithm for delivering IMRT to targets exhibiting two-dimensional rigid target motion in the beam’s eye view” Med. Phys. 35 , 3875-3888 (2008) .
S. Lo, A. Fakiris, L. Papiez, R. Abdulrahman, R. McGarry, M. Henderson, J. Forquer, D. Hoopes, R. Timmerman, “Stereotactic body radiation therapy for early-stage non-small-cell lung cancer” Expert. Rev. Anticancer. Ther. 8, 87-98 (2008).
D. Rangaraj, G. Palaniswaamy and L. Papiez, “DMLC IMRT delivery for targets moving in 2D in Beam’s Eye View”, Med. Phys. 35, 3765 -3778 (2008).
J. H. Heinzerling,.L. Papiez, S. Chien, J. Anderson, K. Forster, G. Zhang, R. D. Timmerman, “Stereotactic Body Radiation Therapy: Evaluation of Setup Accuracy and Targeting Methods for a New Couch Integrated Immobilization System “, Technol. Cancer Res. Treat. 7, 197-206 (2008).
J. H. Heinzerling, J. Anderson, L. Papiez, T, Boike, S. Chien, G. Zhang, R. Abdulrahman, R. D. Timmerman, “Four-dimensional computed tomography scan analysis of tumor and organ motion at varying levels of abdominal compression during stereotactic treatment of lung and liver”, Int. J. Rad. Oncol. Biol. Phys. 70, 1571-1578 (2008).
R. McMahon, L. Papiez, R. Berbeco, S. Nishioka and H. Shirato “An improved MLC control algorithm for delivering IMRT to targets exhibiting two-dimensional rigid target motion in the beam’s eye view” Med. Phys. 35, 3875-3888 (2008).
L. Papiez and R. M. Abolfath, “Variable beam dose rate and DMLC IMRT to moving body anatomy”, Med. Phys. (in print).
Y.Xiao, R.Timmerman, W.Straube, W.Bosch, L.Papiez and J.Galvin “Dosimetric evaluation of heterogeneity corrections for RTOG 0236: stereotactic body radiation therapy of Inoperable stage I/II non-small cell lung cancer” Int. J. Rad. Oncol. Biol. Phys. (submitted).
R. Abolfath and L. Papiez "Protection Strategy of Sensitive Body Organs in Radiation Therapy" Physical Review Letters (submitted)
DeSalles AAF, Medin PM. Functional Spine Radiosurgery. In: Spine Radiosurgery, PC Gerszten and S Ryu, Eds. Thieme, New York, 2008 (IN PRESS)
Solberg TD, Medin PM. Quality Assurance in Spinal Radiosurgery, S Ryu, PC Gerszten, Eds. Thieme, New York (In Press), 2008.
Solberg TD, Kavanagh BD, Medin PM. Image Guided Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy, In: Image Guided and Adaptive Radiation Therapy, R Timmerman, L Xing, Eds. Lippincott, Williams, and Wilkins, Philadelphia (In Press), 2008.
Solberg TD, Kavanagh BD, Medin PM. Stereotactic Body Radiation Therapy: A New Paradigm in Radiotherapy Management of Cancer, J Appl Clin Med Phys (In Press), 2008.
Solberg TD, Medin PM, Mullins J, Li S. Quality assurance of immobilization and target localization systems for frameless stereotactic cranial and extracranial hypofractionated radiotherapy,. Int J Radiat Oncol Biol Phys (in press), 2008.
Rizki A, Weaver VM, Lee SY, Rozenberg GI, Chin K, Myers CA, Bascom JL, Mott JD, Semeiks JR, Grate LR, Mian IS, Borowsky AD, Jensen RA, Idowu MO, Chen F, Chen DJ, Petersen OW, Gray JW, Bissell MJ. A human breast cell model of preinvasive to invasive transition. Cancer Res. 68:1378-87 [2008].
Nagasawa H, Wilson PF, Chen DJ, Thompson LH, Bedford JS, Little JB. Low doses of alpha particles do not induce sister chromatid exchanges in bystander Chinese hamster cells defective in omologous recombination. DNA Repair (Amst). 7:515-22 [2008].
Weterings E, Chen DJ. The endless tale of non-homologous end-joining. Cell Res. 18:114-24 [2008].
Yano K, Morotomi-Yano K, Wang SY, Uematsu N, Lee KJ, Asaithamby A, Weterings E, Chen DJ. Ku recruits XLF to DNA double-strand breaks. EMBO Rep.. 9:91-6 [2008].
Asaithamby A, Uematsu N, Chatterjee A, Story MD, Burma S, Chen DJ. Repair of HZEparticle-
induced DNA double-strand breaks in normal human fibroblasts. Radiat Res. 169:437-46 [2008].
Williams DR, Lee KJ, Shi J, Chen DJ, Stewart PL. Cryo-EM structure of the DNAdependent
protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding. Structure. 16:468-77 [2008].
Yano KI, Chen DJ. Live cell imaging of XLF and XRCC4 reveals a novel view of protein assembly in the non-homologous end-joining pathway. Cell Cycle. 7:1321-5 [2008].
Yu Y, Mahaney BL, Yano K, Ye R, Fang S, Douglas P, Chen DJ, Lees-Miller SP. DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks. DNA Repair (Amst). 7:1680-92 [2008].
Park, C, Papiez, L, Zhang, S, Story, M.D., and Timmerman, R.D. The universal survival curve and single fraction equivalent dose: Useful tools in understanding the potency of ablative radiation therapy. Int. J. Radiat. Onc. Biol. Phys. 70: 847-852, 2008
Kodym, R., Kodym, E., and Story, M.D. Sequence specific activation of TAK1-D by short double-stranded RNAs induces apoptosis in NCI-H460 cells. RNA 14: 535-542, 2008
Klopp, AH, Lu, KH, Broaddus, R., Ramdas, L., Story, M.D., Eiffel, P,, and Jhingran, A., Gene expression changes in cervical squamous cell carcinoma after initiation of chemoradiation and correlation with clinical outcome. Int. J. Radiat. Biol. Phys. 71: 226-236, 2008.
Asaithamby, A., Uematsu, N, Burma, S., Story, M.D., and Chen, D.J. HZE particle-induced DNA double-strand break repair in normal human fibroblasts. Radiat. Res., (in press).
Ding, L.-H., Xie, Y, Park, S., Xiao, G. and Story, M.D. Enhanced identification and biological validation of differential gene expression via Illumina whole genome expression arrays through the use of the model based background correction methodology. Nuc. Acids. Res. (in press). Ramdas, L. Giri, L., Ashorn, C.L., Coombes, K.R., el-Naggar, A., Ang, K.K. and Story, M.D. miRNA expression distinguishes head and neck squamous cell carcinoma from adjacent normal tissue. Head Neck, (accepted).
Park S., Ramnarain DB, Hatanpaa KJ, Mickey ME, Saha D, Paulmurugan R, Madden CJ, Wright PS, Bhai S, Ali MM, Puttaparthi K, Hu W, Elliott JL, Stuve O, Habib AA. The death domain containing kinase RIP1 regulates p27Kip1 levels via a PI3K-Akt-Forkhead pathway. EMBO Report 9: 766-773, 2008
Ding LH, Xie Y, Park S, Xiao G, Story MD. Enhanced Identification and Biological Validation of Differential Gene Expression via Illumina Whole Genome Expression Arrays through the Use of the Model Based Background Correction Methodology. Nucleic Acids Res. 36:e58. 2008
Ramnarain DB, Paulmurugan R, Park S, Mickey BE, Asaithamby A, Saha D, Kelliher MA, Mukhopadhyay P, Banani F, Madden CJ, Wright PS, Chakravarty S, Habib AA. RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR. Cell death differ. 15:344-353. 2008
Ding L. H., Xie Y., Park S., Xiao G., Story M. D. Enhanced Identification and Biological Validation of Differential Gene Expression via Illumina Whole Genome Expression Arrays Through the Use of the Model Based Background Correction Methodology. Nucleic Acids Res. 36(10):e58, 2008 Jun.
Cui Y, Ramnarain DB, Chiang YC, Ding LH, McMahon JS, Denis CL. Genome wide expression analysis of the CCR4-NOT complex indicates that it consists of three modules with the NOT module controlling SAGA-responsive genes. Mol Genet Genomics. 279(4):323-37, 2008 Apr.
Tomimatsu N and Burma S
Rapid IR-induced phosphorylation of ATM substrates in ATM-deficient cells: involvement of ATR and DNA-PKcs Ataxia-telangiectasia workshop 22-26 April 2008
Tomimatsu N , Mukherjee and Burma S Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells the 6th Annual Postdoctoral Poster Session at UTSW
7-12 November 2008
Yajima, H., Lee, K., Zhang, S., Kobayashi, J., and Chen, B.P. DNA Double Strand Break Formation upon UV-Induced Replication Stress Activates ATM and DNA-PKcs Kinases. (J. Mol. Biol. accepted)
Eric Weterings and David J. Chen. ‘The endless tale of non-homologous end-joining.’, Cell Research, 18 (2008), 1, 114-124.
Modulation of the DNA-damage response to HZE particles by shielding. B. Mukherjee, C.V. Camcho, N. Tomimatsu, J. Miller, and S. Burma DNA Repair 7:1717-1730 (2008)
Repair of HZE-partcle-induced DNA double-strand breaks in normal human fibroblasts.
A. Asaithamby, N. Uematsu, A. Chatterjee, M.D. Story, S. Burma, and D.J. Chen Radiation Research 169:437-446 (2008)
Elisabeth Kodym, Reinhard Kodym, Hak Choy, and Debabrata Saha (2008). Sustained metaphase arrest in response to ionizing radiation in a non-small cell lung cancer cell line. Radiation Research;169, 46-58.
Park S, Ramnarain DB, Hatanpaa KJ, Mickey BE, Saha D, Paulmurugan R, Madden CJ, Wright PS, Bhai S , Ali MA, Puttaparthi K, Hu W, Elliott JA, Stuve O and Habib AH (2008). The death domain containing kinase RIP1 regulates p27Kip1 levels via a PI3K-Akt-Forkhead pathway. EMBO Rep. 2008 Aug; 9 (8):766-73.
Michael Story, Reinhard Kodym and Debabrata Saha (2008). Unique molecular, biological and tissue effects with hypofractionated radiotherapy. Semin Radiat Oncol. 2008 Oct;18 (4):244-8.
DB Ramnarain, R Paulmurugan, S Park, BE Mickey, A Asaithamby, D Saha, MA Kelliher, P Mukhopadhyay, F Banani, CJ Madden, PS Wright, S Chakravarty and AA Habib (2008). RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR. Cell Death and Differentiation, 15, 344-353
Elisabeth Kodym, Reinhard Kodym, Aimee Reis, Michael D. Story, Hak Choy and Debabrata Saha (2008). SNS-032 enhances cellular radiosensitivity in quiescent and hypoxic non-small cell lung cancer cells. Submitted to Lung cancer.
M. Aktar Ali, Aimee Reis, Liang-hao Ding, Michael D Story, Amyn A Habib and Debabrata Saha (2008). SNS-032 inhibits hypoxia mediated glioblastoma cell invasion by downregulating hypoxia inducible factor-1 expression. Submitted to Int J Oncology.
Sustained metaphase arrest in response to ionizing radiation in a non-small cell lung cancer cell line.
Kodym E, Kodym R, Choy H, Saha D. Radiat Res. 2008 Jan;169(1):46-58. PMID: 18159951 [PubMed - indexed for MEDLINE] Kodym R, Kodym E, Story MD.
RNA. 2008 Mar;14(3):535-42. Epub 2008 Jan 29.
PMID: 18230764 [PubMed - indexed for MEDLINE]
Abstracts
C Ding, X Li, Y Yang, et. al, “SU-DD-A3-06: The Impact of Probe Angle and Tissue Elastic Module in Ultrasound-Guided Prostate IMRT”, Med. Phys. 35, pp. 2635, 2008
X Li, C Ding, Y Yang, et. al, “SU-GG-J-26: An Accuracy Improvement of Ultrasound-CT Modality for Ultrasound Guided Prostate IMRT Planning”, Med. Phys. 35, 2684, 2008
Choy, H. University of Miami Sylvester Cancer Center Thoracic Conference. “Optimal Treatment of Stage IIIB NSCLC”. Miami, FL 1/10/2007
Choy, H. Miami Oncology Group. “Optimal Treatment of Stage IIIB NSCLC”. Miami, FL 1/11/2007
Choy, H. Memorial Cancer Center Grand Rounds. “Optimal Treatment of Stage IIIB NSCLC”. Hollywood, FL 1/12/2007
Choy, H. National Cancer Center of Korea Grand Rounds. “Recent Advances in Radiation Oncology” Seoul, Korea 9/5/2007
Choy, H. Coborn Cancer Center Grand Rounds. “Optimal Treatment of Stage IIIB NSCLC”. St Cloud, MN 9/19/2007
Choy, H. Minnesota Hematology/Oncology Invited Lecture Series. “State of the Art Therapy in Unresectable Stage III NSCLC”. Maplewood, MN 9/20/2007
Choy, H. University of Minnesota Thoracic Conferences. “Management of the Early Stage Non Small Cell Lung Cancer: Past, Present and Future”. Minneapolis, MN 9/20/2007
Bourke VA, Zhao D, Gilio J, Chang CH, Jiang L, Hahn EW, Mason RP: Correlation of Radiation Response with Tumor Oxygenation in the Dunning Prostate R3327-AT1 Tumor, Int. J. Radiation Oncology Biol. Phys. 67, 1179-1186 (2007).
C Ding, X Li, M. S. Huq, et. al, “The Effect of Respiratory Cycle and Radiation Beam-on Timing on the Dose Distribution of Free-Breathing Breast Treatment Using Dynamic IMRT Technique”, Med. Phys., Vol. 34, (9), pp. 3500-3509, 2007
C. B. Saw, Y. Yang, F. Li, N. J. Yue, C. Ding, et. al, “Performance Characteristics and Quality Assurance Aspects of Kilovoltage Cone-Beam CT on Medical Linear Accelerator”, Medical Dosimetry, vol. 32, (2) pp. 80-85, 2007.
R. Timmerman, B.Kavanagh, L. Cho, L. Papiez, L. Xing, “Stereotactic Body Radiation Therapy in Multiple Organ Sites”, Journal of Clinical Oncology, 25, 947-952 (2007) .
L. Papiez, R. McMahon and R.Timmerman, “4D IMRT planning and delivery – formulation and preliminary results”, in “The Radiotherapy Dynamic”, XV th International Conference on the Use of Computers in Radiation Therapy, vol.1, Eds. J.P. Bissonnette, D. Bahig, University of Toronto, Toronto, p.298 (2007).
L. Papiez, “Dosimetric Considerations for Stereotactic Body Radiotherapy Delivery” in “Robotic Radiosurgery – Treating Tumors that Move with Respiration”, Springer, New York (2007).
R. McMahon, L. Papiez and D. Rangaraj, “Dynamic-MLC leaf control utilizing on-flight intensity calculations : A robust method for real-time IMRT delivery over moving rigid targets”, Med. Phys. 34, 3211-3223 (2007).
R. McMahon, L. Papiez and G. Sandison, “Addressing relative motion of tumors and normal tissue during dynamic MLC tracking delivery”, Australas. Phys. Eng. Sci. Med. 30, 331-336 (2007).
L. Papiez, R. McMahon and R. Timmerman, “4D DMLC leaf sequencing to minimize organ at risk dose in moving anatomy”, Med. Phys. Lett. 34, 4952-4956 (2007).
Jahan R, Solberg TD, Lee D, Medin P, Tateshima S, DeSalles A, Sayre J, Vinters H, Vinuela F. Arteriovenous Malformation Model for Stereotactic Radiosurgery Research. Neurosurgery 61(1):152-59, 2007.
Fang L, Wang Y, Du D, Yang G, Tak Kwok T, Kai Kong S, Chen B, Chen DJ, Chen Z.
Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA doublestrand
break repair. Cell Res. 17:100-16 [2007].
Chen BP, Uematsu N, Kobayashi J, Lerenthal Y, Krempler A, Yajima H, Lobrich M, Shiloh Y, Chen DJ. Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. J Biol Chem. 282:6582-7 [2007].
Tomimatsu N, Tahimic CG, Otsuki A, Burma S, Fukuhara A, Sato K, Shiota G,Oshimura
M, Chen DJ, Kurimasa A. Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks. J Biol Chem. 282:10138-45 [2007].
Li J, Sejas DP, Burma S, Chen DJ, Pang Q. Nucleophosmin suppresses oncogeneinduced
apoptosis and senescence and enhances oncogenic cooperation in cells with genomic instability. Carcinogenesis. 28:1163-70 [2007].
Uematsu N, Weterings E, Yano K, Morotomi-Yano K, Jakob B, Taucher-Scholz G, Mari PO, van Gent DC, Chen BP, Chen DJ. Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks. J Cell Biol. 177:219-29 [2007].
Das AK, Chen BP, Story MD, Sato M, Minna JD, Chen DJ, Nirodi CS.Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma. Cancer Res. 67:5267-74 [2007].
Ogawa K, Boucher Y, Kashiwagi S, Fukumura D, Chen D, Gerweck LE.Influence of tumor cell and stroma sensitivity on tumor response to radiation. Cancer Res. 67:4016-21 [2007].
Kodym E, Kodym R, Chen BP, Chen DJ, Morotomi-Yano K, Choy H, Saha D.DNAPKcs- dependent modulation of cellular radiosensitivity by a selective cyclooxygenase-2 13 inhibitor. Int J Radiat Oncol Biol Phys. 69:187-93 [2007].
Weterings E, Chen DJ. DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys? J Cell Biol. 179:183-6 [2007].
Chen DJ, Nirodi CS. The epidermal growth factor receptor: a role in repair of radiationinduced
DNA damage. Clin Cancer Res. 13:6555-60 [2007]
Das, A.K., Sato, M. Peyton, M., Chen, B.P., Chen, D.J, Gazdar, A.F., Minna, J.D. and Nirodi, C.S. (2007) Somatic mutations in the tyrosine kinase domain abrogate a critical radioprotective function of EGFR in Non-small Cell Lung Cancers. Cancer Research, 67, (11), 5267-5274
Chen, D. J. and Nirodi, C.S. (2007) “The Epidermal Growth Factor Receptor: A Role in Repair of Radiation-induced DNA Damage”. Clin Cancer Res 13: 6555-60
Das, A.K., Chen, B.P., Story, M.D., Sato, M., Minna, J.D., Chen, D.J. and Nirodi, C.S. Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma. Cancer Res. 67: 5267-5274, 2007
Tomimatsu N, Tahimic CG, Otsuki A, Burma S, Fukuhara A, Sato K, Shiota G, Oshimura M,
Chen DJ, Kurimasa A. Ku70/80 modulates ATM and ATR signaling pathways in response to
DNA double-strand breaks. J Biol Chem. 2007 Feb 1; on line
Fang, L., Wang, Y., Du, D., Yang, G., Kwok, T., Kong, S., Chen, B.P., Chen, D.J., Chen, Z. 2007. Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair. Cell Research. 17:100-116.
Chen, B.P., Uematsu, N., Kobayashi, J., Lerenthal, Y., Yajima, H., Krempler, A., Lobrich, M., Shiloh, Y., Chen, D.J. 2007. ATM is essential for phosphorylation of DNA-PKcs at T2609 cluster upon DNA double strand break. J. Biol. Chem. 282: 6582-6587.
Uematsu, N., Weterings, E., Yano, K., Morotomi-Yano, K., Jakob, B., Taucher-Scholz, G., Mari, P.O., van Gent, D.C., Chen, B.P., and Chen, D.J. 2007. Autophosphorylation of DNA-PKcs regulates its dynamics at DNA double-strand breaks. J. Cell Biol. 177:219-29.
Das, A.K., Chen, B.P., Story, M.D., Minna, J.D., Chen, D.J., and Nirodi, C.S. 2007. Somatic mutations in the tyrosine kinase domain of EGFR abrogate EGFR-mediated radio-protection in non-small cell lung carcinoma. Cancer Res. 67: 5267-74
Kodym, E., Kodym, R., Chen, B.P., Chen, D.J., Morotomi-Yano, K., Choy, H., and Saha, D. 2007. DNA-PKcs Dependent Modulation of Cellular Radiosensitivity by a Selective Cyclooxygenase-2 Inhibitor. Int. J. Radiation Oncology Biol. Phys. 69:187-93.
N. Tomimatsu, G.G. Tahimic, A. Otsuki, S. Burma, A. Fukuhara, K. Sato, G. Shiota, M. Oshimura, D.J. Chen, and A. Kurimasa . Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double-strand breaks. Journal of Biological Chemistry 282:10138-10145 (2007)
J. Li, D.P. Sejas, S. Burma, D.J. Chen, and Q. PangNucleophosmin suppresses oncogene-induced apoptosis and senescence and enhances oncogenic cooperation in cells with genomic instability.
Carcinogenesis 28:1163-1170 (2007)
M Aktar Ali, Hak Choy and Debabrata Saha (2007). SNS-032 prevents tumor cell induced angiogenesis by inhibiting vascular endothelial growth factor. Neoplasia; 9, 370-381
Elisabeth Kodym, Reinhard Kodym, Benjamin P. Chen, David J. Chen, Keiko Morotomi-Yano, Hak Choy and Debabrata Saha (2007). Modulation of Radiosensitivity by Celecoxib is DNA-PK dependent (2007). International Journal of Radiation Oncology Biol. Phys; 69, 187-193.
Robert Timmerman, Michael Bastasch, Debabrata Saha, Ramzi Abdulrahaman, William Hitson and Michael Story (2007). Optimizing dose and fractionation for stereotactic body radiation therapy: Normal tissue and tumor control effects with large dose per fraction. Front Radiother Oncol Basel, Karger; 40:346-359
C Ding, X Li, M. S. Huq, et. al, “The Effect of Respiratory Cycle and Radiation Beam-on Timing on the Dose Distribution of Free-Breathing Breast Treatment Using Dynamic IMRT Technique”, Med. Phys., Vol. 34, (9), pp. 3500-3509, 2007
C. B. Saw, Y. Yang, F. Li, N. J. Yue, C. Ding, et. al, “Performance Characteristics and Quality Assurance Aspects of Kilovoltage Cone-Beam CT on Medical Linear Accelerator”, Medical Dosimetry, vol. 32, (2) pp. 80-85, 2007.
Abstracts
C Ding, X Li, Y Yang, et. al, “TU-EE-A3-01: Evaluating the Impact of Probe Depression On Prostate Displacement in Ultrasound-Guided Prostate IMRT Treatment”, Med. Phys. 34, 2564, 2007
X Li, C Ding, Y Yang, et. al, “TH-D-M100F-09: Ultrasound-Guided Prostate IMRT Planning: An Ultrasound-CT Application”, Med. Phys. 34, pp. 2638, 2007
Peer Reviewed
L. Papiez, “Dosimetric Considerations for Stereotactic Body Radiotherapy Delivery” in “Robotic Radiosurgery – Treating Tumors that Move with Respiration”, Springer, New York (2007).
R. McMahon, L. Papiez and D. Rangaraj, “Dynamic-MLC leaf control utilizing on-flight intensity calculations : A robust method for real-time IMRT delivery over moving rigid targets”, Med. Phys. 34, 3211-3223(2007).
R. McMahon, L. Papiez and G. Sandison, “Addressing relative motion of tumors and normal tissue during dynamic MLC tracking delivery”, Australas. Phys. Eng. Sci. Med. 30, 331-336 (2007).
L. Papiez, R. McMahon and R. Timmerman, “4D DMLC leaf sequencing to minimize organ at risk dose in moving anatomy”, Med. Phys. Lett. 34, 4952-4956 (2007).
Cellular signal transduction events as a function of linear energy transfer (LET). Fürweger C, Hajek M, Vana N, Kodym R, Okayasu R. Radiat Prot Dosimetry. 2007;126(1-4):418-22. Epub 2007 Jun 18.
PMID: 17576650 [PubMed - indexed for MEDLINE]
DNA-PKcs-dependent modulation of cellular radiosensitivity by a selective cyclooxygenase-2 inhibitor.
Kodym E, Kodym R, Chen BP, Chen DJ, Morotomi-Yano K, Choy H, Saha D. Int J Radiat Oncol Biol Phys. 2007 Sep 1;69(1):187-93. PMID: 17707272 [PubMed - indexed for MEDLINE]
