Yi Liu, Ph.D. Associate Professor Voice (214) 645-6033 Fax (214) 645-6049 Room ND13.214AA Yi.Liu@UTSouthwestern.edu The University of Texas Southwestern Medical Center at Dallas Department of Physiology 5323 Harry Hines Boulevard Dallas, TX  75390-9040

Publications:

Cheng P, Y Yang, C Heintzen and Y Liu (2001) Coiled-coil domain mediated FRQ-FPQ interaction is essential for its circadian clock function in Neurospora.  EMBO J, 20:101-8

Cheng P, Y Yang and Y Liu (2001) Interlocked feedback loops contribute to the robustness of the Neurospora cirdadian clock. Proc Natl Acad Sci USA 98:7408-13

Yang Y, P Cheng, G Zhi and Y Liu (2001) Identification of a calcium/calmodulin-dependent protein kinase that phosphorylates the Neurospora circadian clock protein FREQUENCY. J Biol Chem 276:41064-72

Cheng P, Y Yang, KH Gardner and Y Liu (2002) PAS domain mediated WC-1/WC-2 interaction is essential for maintaining the steady state level of WC-1 and the function of both proteins in circadian clock and light responses of Neurospora. Mol Cell Biol 22:517-24

Yang Y, P Cheng and Y Liu (2002) Regulation of the Neurospora circadian clock by casein kinase II. Genes & Development 15:994-1006

He* Q, P Cheng*, Y Yang, L Wang, KH Gardner and Y Liu (2002) White Collar-1, a DNA-binding transcription factor and a light sensor. Science 297:840-3 *equal contribution)

Froehlic AC, Y Liu, JJ Loros and JC Dunlap (2002) White Collar-1, a circadian blue light photoreceptor, binds to the frequency promoter. Science 297:815-9

Cheng P, Y Yang, L Wang, Q He and Y Liu (2003) WHITE COLLAR-1, a multifunctional Neurospora protein involved in the circadian feedback loops, light sensing, and transcription repression of wc-2. J Biol Chem 278:3801-8

Cheng P, Q He, Y Yang, L Wang, and Y Liu. (2003) Functional conservation of light, oxygen, or voltage domains in light sensing. Proc Natl Acad Sci USA 100:5938-43

Liu Y (2003) Molecular mechanisms of entrainment in the Neurospora circadian clock. J Biol Rhythms 18:195-205

Yang Y, P Cheng, Q He, L Wang and Y Liu (2003)    Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock. Mol Cell Biol. 23:6221-8

Liu Y, Q. He, and P. Cheng. (2003) Photoreception in Neurospora, a tale of two White Collar proteins. Cell Mol Life Sci 60:2131-8

He*, Q., P Cheng*, Y Yang, Q He, H Yu and Y Liu.   (2003)   FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation. EMBO J 22:4421-30 (*equal contribution)

Yang Y, P Cheng, Q He, P Wrage, O Yarden and Y Liu (2004) Distinct roles for PP1 and PP2A in the Neurospora circadian clock.  Genes & Dev 18:155-60

Min, H., Y. Liu, C. H. Johnson, and S. S. Golden. (2004) Phase Determination of Circadian Gene Expression in Synechococcus elongatus PCC 7942. J. Biol. Rhythms 19:103-112.