The Southwestern NMR Center for in vivo Metabolism - National Center for Research Resources (NCRR) is involved in the development and application of new magnetic resonance methods for monitoring physiology and biochemistry in vivo.
Major research topics include:
- Innovative applications of stable isotopes (2H and 13C)
- Modern NMR methods to measure flux through biochemical pathways in animals and human subjects
- The design of new lanthanide-based agents that report features of the intra- and extracellular environment
The Center is supported by the National Institutes of Health (NIH) National Center for Research Resources which funds technology development and application to humans. Through the National Institute of Diabetes and Digestive and Kidney Diseases, the technology is also made available to the study of mice under the Mouse Metabolic Phenotyping Center initiative.
The Research Activity section, in the left menu bar, provides brief descriptions of the activities taking place at this center. These consist of:
- Technology development in NMR spectroscopy and imaging methods
- Application of such technology in the study of humans and animals
- Developing and providing software for determining metabolic fluxes
- An annual symposium to discuss recent developments and explore how they can be used in different areas of research
- Training in the technology for outside users
- Opportunities for collaborations
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