Research Overview:
Study of the lipodystrophy syndromes as a model to understand the mechanisms of insulin resistance. Particular interest in the role of leptin as a mediator between fat and insulin action, and in its potential therapeutic role. Involved in clinical trials of recombinant leptin therapy for patients with lipodystrophy. Have also been working on trying to understand the mechanism of HIV-associated lipodystrophy, and its therapeutic options.
Research Interests:
- Lipodystrophy syndromes
- Leptin biology and therapeutics
