Ramesh Saxena, M.D., Ph.D.
> Assistant Professor of Medicine

Research Interests:

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	Recurrent MPGN in a renal allograft before (upper) and after (lower) treatment with plasmapheresis. Not resolution of subendothelial deposits.

Icodextin in high peritoneal transporters. Kremezin study in patients with chronic kidney disease. SV40 in focal segmental glomerulosclerosis. Molecular studies in lupus nephritis.

Selected Publications:

Saxena R, Frankel WL, Sedmak DD, Falkenhain ME, Cosio FG. Recurrent type I membranoproliferative glomerulonephritis in a renal allograft: successful treatment with plasmapheresis. Am J Kidney Dis. 2000 Apr;35(4):749-52.

Rovin BH, Lu L, Saxena R. A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression. Biochem Biophys Res Commun. 1999 Jun 7;259(2):344-8.

Ganz MB, Abu-Nader R, Saxena R, Grond J. Protein kinase C beta II isoform is up-regulated in human proliferative glomerulonephritis. Exp Nephrol. 1997 May-Jun;5(3):225-32.

Ganz MB, Saksa B, Saxena R, Hawkins K, Sedor JR. PDGF and IL-1 induce and activate specific protein kinase C isoforms in mesangial cells. Am J Physiol. 1996 Jul;271(1 Pt 2):F108-13.

Saxena R, Saksa BA, Hawkins KS, Ganz MB. Protein kinase C beta I and beta II are differentially expressed in the developing glomerulus. FASEB J. 1994 Jun;8(9):646-53.

Saxena R, Saksa BA, Fields AP, Ganz MB. Activation of Na/H exchanger in mesangial cells is associated with translocation of PKC isoforms. Am J Physiol. 1993 Jul;265(1 Pt 2):F53-60.

Updated September !4, 2007                                        Created by Megan Johnson

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