The Neuropsychology Laboratory at The University of Texas Southwestern Medical Center is involved in a wide variety of research projects that include many areas of neuropsychiatry.  Our research often involves collaboration with investigators from departments across the medical school, including psychiatry, neurology, neurosurgery, nuclear medicine, and radiology.  Neuropsychology is an integral part of the NIA-funded Alzheimer's Disease Center on campus and is involved in studies of Mild Cognitive Impairment (MCI), Frontotemporal Dementia and early Alzheimer's Disease (AD).  In particular, we are interested in the early detection, differential diagnosis, and progression of cognitive change in MCI and AD.  Other primary areas of focus include:

• Neuropsychological correlates of brain imaging in neuropsychiatric populations
• Normal aging and the early detection and differential diagnosis of dementia
• Characterization of lateralized epilepsy
• Use of cognitive algorithms in neurodiagnosis
• Cognitive test development (including IADL and executive function measures)
• Psychometric properties of neurocognitive tests
• Neuropsychological effects of depression and bipolar illness
• Neurocognitive functioning and rehabilitation in schizophrenia
• Cognitive function in HIV
• Traumatic Brain Injury
• Psychoeducational intervention and outcome following neurosurgical intervention
• Functional MRI and Functional Connectivity MRI (fcMRI)

Neuropsychology collaborative research includes the following funded projects:

• Early Randomization Surgical Epilepsy Trial (ERSET)
• Comparing Three Electrode Placements to Optimize ECT
• Magnetic Seizure Therapy (MST) for the Treatment of Major Depression
• Regional Cerebral Blood Flow and Cognition Enhancement in Schizophrenia
• Secondary Prevention of Small Subcortical Stroke (SPS3)
• Traumatic Brain Injury Model Systems
• Hippocampal Function During Corticosteroid Therapy