Molecular mechanisms and translational research in kidney cancer
A postdoctoral position is available in the Brugarolas lab for entrepreneurial individuals pursuing a career in Academia who are interested in Cancer Biology.
The Brugarolas lab focuses on understanding kidney cancer. Specifically we are interested in:
- Dissecting pathways involved in kidney cancer development, such as the mTOR pathway.
- The discovery, using genomic platforms, of new pathways implicated in the pathogenesis of kidney cancer.
- The development of novel paradigms for the evaluation of molecularly targeted therapies for kidney cancer.
To attain these goals, multiple approaches are utilized in the lab. Ongoing projects include: an RNAi screen of the Drosophila kinome, affinity chromatography studies to identify interacting proteins, genomic analyses of patient tumor samples, a synthetic lethal screen to identify tumor specific targets, molecular studies of drugs approved for use in patients with kidney cancer, as well as a variety of cellular and molecular biology projects. In addition, the laboratory works with several genetically engineered mouse models harboring mutations in various tumor suppressor genes including Vhl, Tsc1, Tsc2 as well as REDD1.
The laboratory offers an extraordinarily rich environment that encompasses both basic and translational research for highly motivated individuals interested in Cancer Biology.
For more information see: http://www4.utsouthwestern.edu/brugarolaslab/
Position requirements: candidates should hold an MD/PhD or PhD degree and be interested in a career in Academia.
Interested individuals should send the following information:
- A statement of interest explaining the reasons why the candidate is interested in the position and how the position might further the candidate’s career goals.
- An updated CV.
- Names and contact information for 3 professional references.
James Brugarolas, M.D., Ph.D.
Assistant Professor
c/o Bradley Hicks
Sr. Administrative Assistant
5323 Harry Hines Blvd.
Dallas, Tx 75390-9133
Bradley.Hicks@utsouthwestern.edu
UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer
