The Department of Radiation Oncology is a part of one of the world's leading medical research institutions, UT Southwestern Medical Center, which provides an ideal, state-of-the-art environment for conducting research and clinical trials.
The clinical treatment trials offered by our department and supervised by our Director of Clinical Research, Dr. Robert Timmerman, test new treatments such as new drugs, new approaches to radiation therapy, as well as new methods of treatment. We encourage you to consider participating in a clinical trial as a treatment option. If you are well informed of all treatment options available to you, then you and your doctor will be able to decide which treatment is best for you. If you would like more information about our clinical trials or specific studies currently available, please contact our Clinical Research office at (214) 648-5536.
Clinical Trials by Disease Site
Clinical trials may be available in the following categories of cancer sites:
▶▶▶ Click here for a complete listing of current
Clinical Trials By Disease Site.
What is a Clinical Trial?
Through research and clinical trials, the Department of Radiation Oncology at UT Southwestern Medical Center strives to advance the treatment of a number of cancers. It is our priority to insure scientific integrity, privacy and ethical conduct in all clinical trials. As a patient being treated in the department's clinic, Moncrief Radiation Oncology Center, you may be eligible to take part in a clinical trial.
A clinical trial is a research study that is conducted in a medical setting such as a clinic or hospital. It usually involves the testing of a new medication, treatment, or device that is not yet approved by the Food & Drug Administration (FDA) for routine use. The purpose of a clinical trial is to find out if a new medical treatment is safe and effective and which approaches are most successful in fighting cancer. All medications and treatments in use today were first shown to be effective in clinical trials. Clinical trials can also explore if drugs or treatments that are already available in pharmacies are effective for other diseases than those already approved by the FDA. Clinical studies can also explore how drugs interact with the body. New and better treatments for cancer will be discovered only through the continued support of patients who participate in clinical trials.
Who is eligible for a Clinical Trial?
Patients who qualify for a clinical trial decide, with the advice of their physician, whether to participate in the study. How a treatment will work for a patient in a trial cannot be known ahead of time. Therefore, the patient should be aware of both the risks and benefits of clinical trials before making a decision. You will never be placed on a clinical trial without your knowledge or permission. All qualified patients involved in clinical trials sign consent forms before the study begins.
Before a new treatment is tested with patients, it is carefully studied for several years in the laboratory and tested for safety. This research identifies the new methods most likely to succeed and, as much as possible, shows how to use them safely and effectively. Then, clinical trials undergo a rigorous approval process both by the Federal Drug Administration (FDA) and by committees of UT Southwestern physicians. One of these committees also includes patient advocates to ensure that patients are represented and that their rights are fully considered in each trial situation. Although there is always a possibility that a new treatment will be disappointing, the researchers and physicians who approve a study have reason to believe that it will be as good as, or better than, current treatments. If you qualify, we hope that you and your family will consider participating in this worthwhile endeavor. Please do not hesitate to talk to your physician about clinical trials that may be available for your participation.
How can you enroll in a trial and what should you expect?
A preliminary screening visit is scheduled to discuss the details of the study with the potential volunteer and determine if he/she is eligible to participate. The nurse or physician will explain the study and the procedures you will need to follow and answer any question you may have. This process is called informed consent and is essential before any volunteer is enrolled in any clinical trial. In addition, a full medical history is obtained and a physical exam and lab testing is done to make sure there are no contraindications for your participation in the clinical trial. All clinical trials require a time commitment and study schedules vary depending on the individual study.
What information do you need to decide whether or not to enroll in a trial?
You need to inform yourself about: 1) The purpose of the study, 2) How long the study will last and what procedures will be done as part of the research study, 3) Potential risks or discomforts that may be associated with these procedures, including additional treatment costs, if any, 4) What other treatments are available should you not decide to participate in the study.
Are investigational treatments better than currently available ones; are they safe?
Clinical trials are done with the hope that the new treatment will be as effective, or more effective than currently available treatments, but this is not known. By definition, if we are doing a study, it is because we do not know if it is more effective, and there is a chance that it will be less effective, than current treatment. Similarly, clinical trials are designed with safety in mind, and known risks are explained in the consent form. However, there may be risks that are not known at the time the study is started.
What are the rights of a Clinical Trial volunteer?
1) You should be adequately informed of the study and be given the chance to ask any questions
2) Participation in any clinical trial is voluntary.
3) Any information obtained in a clinical trial remains confidential and is shared only with those involved in the study unless authorized by the participant. Just like any other medical record, a research record may be inspected by the FDA, other federal regulatory authorities, and other legally authorized parties.
How do I sign up for a Clinical Trial?
Call our Clinical Trials information line at (214) 648-5536.
Clinical Trial Resources
