|  The Department of Radiation Oncology enrolls as many as 80 new patients each year in clinical trials. Our faculty members hold leadership positions in the Radiation Therapy Oncology Group (RTOG), which develops and oversees all national radiation oncology trials funded by the National Cancer Institute.
Click on the study number for expanded clinical trial information.
(Updated 11/06/09)
| Brain |
A Randomized, Phase III, Double-Blind, Placebo-Controlled Trial of Memantine for Prevention of Cognitive Dysfunction in Patients Receiving Whole-Brain Radiotherapy
RTOG 0614
Principal Investigator: Lucien Nedzi, M.D. -- Coordinator: Jessica Crockett
Local Therapy for Limited Metastatic Disease to the Brain: A Phase II Study of Surgery, SRS and SRT in Favorable Patients
LN-01
Principal Investigator: Lucien Nedzi, M.D. -- Coordinator: Jessica Crockett
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| Breast |
A Randomized Phase II Study of Conventional Whole Breast Irradiation (WBI) Versus Partial Breast Irradiation (PBI) for Women with Stage 0, I or II Breast Cancer
RTOG 0413
Principal Investigator: Ann Spangler, M.D. -- Coordinator: Jessica Crockett
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| Head and Neck |
A Phase I/II Study of Nab-Paclitaxel, Cisplatin and Cetuximab with Concurrent Radiation Therapy for Local-Regionally Advanced Head-and-Neck Squamous Cell Carcinoma (HNSCC)
Abraxane/ABX 236-HNO8US
Principal Investigator: Lucien Nedzi, M.D. -- Coordinator: Susan Cooley, RN
A Phase II Multi-Center Study of Concomitant Cetuximab and Cisplatin with Re-irradiation Using Intensity-Modulated Radiotherapy (IMRT) in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck
BMS CA 225314
Principal Investigator: Lucien Nedzi, M.D. -- Coordinator: Irma Charles, M.S.
A Randomized Phase II Trial of Chemoradiotherapy Versus Chemoradiotherapy and Vandetanib For High-Risk Postoperative Advanced Squamous Cell Carcinoma of the Head and Neck
RTOG 0619
Principal Investigator: Lucien Nedzi, M.D. -- Coordinator: Jessica Crockett
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| Lung (Thoracic) |
Small Cell Lung Cancer
A Phase III Comparison of Thoracic Radiotherapy Regimes With Cisplatin and Etoposide In Limited Small Cell Lung Cancer
CALGB 30610/RTOG 0538
Principal Investigator: Hak Choy, M.D. -- Coordinator: Laurin Loudat
Non-Small Cell Lung Cancer
* Adjuvant / Neoadjuvant / Prevention
A Phase II Trial of Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Patients with Operable Stage I/II Non-Small Cell Lung Cancer
RTOG 0618
Principal Investigator: Robert Timmerman, M.D. -- Coordinator: Irma Charles, MS
*Locally Advanced (III) or Inoperable (I/II)
A Randomized Phase III Comparison of Standard-Dose (60 Gy) Versus High-Dose (74 Gy) Conformal Radiotherapy With Concurrent and Consolidation Carboplatin/Paclitaxel /- Cetuximab (IND #103444) In Patients With Stage IIIA/IIIB Non-Small Cell Lung Cancer
RTOG 0617
Principal Investigator: Hak Choy, M.D. -- Coordinator: Laurin Loudat
Seamless Phase I/II Study of Stereotactic Body Radiotherapy (SBRT) For Early Stage, Centrally Located Non-Small Cell Lung Cancer (NSCLC) In Medically Inoperable Patients
RTOG 0813
Principal Investigator: Robert Timmerman, M.D. -- Coordinator: Irma Charles, M.S.
Phase I Study of Accelerated Hypofractionated Image-Guided Radiation Therapy (IGRT) in Patients with Stage II-IV Non-Small Cell Lung Cancer and Poor Performance Status
072009-061
Principal Investigator: Robert Timmerman, M.D. -- Coordinator: Laurin Loudat
A Randomized Phase I/II Study of Vandetanib in Combination With High Dose Chemoradiation in Patients With Stage IIIA/B Non-Small Lung Cell Cancer (NSCLC)
062009-042
Principal Investigator: Hak Choy, M.D. -- Coordinator: Irma Charles
*Metastatic (2 or more)
A Phase II Trial of Erlotinib (Tarceva®) In Combination With Stereotactic Body Radiation Therapy (SBRT) For Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
42007003
Principal Investigator: Robert Timmerman, M.D. -- Coordinator: Irma Charles, M..S
Non-Therapeutic
Bold Contrast Magnetic Resonance Imaging (MRI) of Lung Tumors: Physiological Characterization of Lung Cancer
SCCC-01508
Principal Investigator: Robert Timmerman, M.D. -- Coordinator: Irma Charles, MS
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| Prostate |
A Phase I and II Study of Stereotactic Body Radiation Therapy (SBRT) for Low and Intermediate Risk Prostate Cancer
62006010
Principal Investigator: Robert Timmerman, M.D. -- Coordinator: Susan Cooley, RN
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| Spine |
A Phase II Study of Stereotactic Body Radiation Therapy and Vertebroplasty for Localized Spine Metastasis
SCCC-03Z08
Principal Investigator: Robert Timmerman, M.D. -- Coordinator: Susan Cooley, RN
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