Arnold, Michael (entered program 1999)
Potthoff MJ, Wu H, Arnold MA, Shelton JM, Backs J, McAnally J, Richardson JA, Bassel-Duby R, Olson EN: Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. J Clin Invest 117(9): 2459-2467, 2007.
Arnold MA, Kim Y, Czubryt MP, Pham D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN: MEF2c transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell 12(3): 377-389, 2007.
Arnold MA, Kim Y, Czubryt MP, Pham D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN: MEF2c transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell 12(3): 377-389, 2007.
Haberland M, Arnold MA, McAnally J, Phan D, Kim Y, Olson EN: Regulation of HDAC9 gene expression by MEF2 establishes a negative-feedback loop in the transcriptional circuitry of muscle differentiation. Mol Cell Biol 27(2): 518-525, 2007.
Davis CA, Haberland M, Arnold MA, Sutherland LB, McDonald OG, Richardson JA, Childs G, Harris S, Owens GK, Olson EN: PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells. Mol Cell Biol 26(7): 2626-2636, 2006.
Durham JT, Brand OM, Arnold M, Reynolds JG, Muthukumar L, Weiler H, Richardson JA, Naya FJ: Myospryn is a direct transcriptional target for MEF2A that encodes a striated muscle, {alpha}-actinin-interacting, costamere-localized protein. J Biol Chem 281: 6841-6849, 2006.
Nakagawa O, Arnold M, Nakagawa M, Hamada H, Shelton JM, Kusano H, Harris TM, Childs G, Campbell KP, Richardson JA, Nishino I, Olson EN: Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2. Genes Dev 19: 2066-2077, 2005.
Bush E, Fielitz J, Melvin I, Martinez-Arnold M, McKinsey TA, Plichta R, Olson EN: A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway. Proc Natl Acad Sci USA 101: 2870-2875, 2004.
Astle, John (2003)
Kathiriya IS, King IN, Murakami M, Nakagawa M, Astle JM, Gardner KA, Gerard RD, Olson EN, Srivastava D, Nakagawa O: Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism.
J Biol Chem. 2004 Dec 24;279(52):54937-43. Epub 2004 Oct 12.
Benavides, David (2000)
Hawasli AH, Benavides DR, Nguyen C, Kansy JW, Hayashi K, Chambon P, Greengard P, Powell CM, Cooper DC, Bibb JA: Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nat Neurosci 10(7): 880-886, 2007.
Benavides DR, Bibb JA: Role of Cdk5 in drug abuse and plasticity.
Ann N Y Acad Sci. 1025: 335-344, 2004.
Beswick, Tracy Clyne (2002)
Beswick TC, Willert EK, Phillips MA: Mechanisms of allosteric regulation of Trypanosoma cruzi S-adenosylmethionine decarboxylase. Biochemistry 45(25): 7797-7807, 2006.
Clyne T, Kinch LN, Phillips MA: Putrescine activation of Trypanosoma cruzi S-adenosylmethionine decarboxylase. Biochem 41(44): 13207-13216, 2002.
Bhoj, Vijay (2005)
Tennakoon DK, Mehta RS, Ortega SB, Bhoj V, Racke MK, Karandikar NJ: Therapeutic induction of regulatory, cytotoxic CD8 T cells in multiple sclerosis. J Immunol 176(11): 7119-7129, 2006.
Chen ZJ, Bhoj V, Seth RB: Ubiquitin, TAK1 and IKK: is there a connection? Cell Death Differ 13(5): 687-692, 2006.
Bingham, Nathan (1999)
Reuter AL, Goji K, Bingham NC, Matsuo M, Parker KL: A novel mutation in the accessory DNA-binding domain of human steroidogenic factor 1 causes XY gonadal dysgenesis without adrenal insufficiency. Europ J Endocrin 157(2): 233-238, 2007.
Bingham NC, Verma-Kurvari S, Parada LF, Parker KL: Development of a steroidogenic factor 1/Cre transgenic mouse line. Genesis: J Genet & Devel 44(9): 419-424, 2006.
Li Y, Choi M, Cavey G, Daugherty J, Suino K, Kovach A, Bingham NC, Kliewer SA, Xu HE
Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1.
Mol Cell. 2005 Feb 18;17(4):491-502.
Correa RV, Domenice S, Bingham NC, Billerbeck AE, Rainey WE, Parker KL, Mendonca BB
A microdeletion in the ligand binding domain of human steroidogenic factor 1 causes XY sex reversal without adrenal insufficiency.
J Clin Endocrinol Metab. 2004 Apr;89(4):1767-72.
Bodemann, Brian (2004)
Whitehurst AW, Bodemann BO, Cardenas J, Ferguson D, Girard L, Peyton M, Minna JD, Michnoff C, Hao W, Roth MG, Xie XJ, White MA: Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature 446(7137): 815-819, 2007.
Chan, Alice (1999)
Chan AY, Westcott JM, Mooney JM, Wakeland EK, Schatzle JD: The role of SAP and the SLAM family in autoimmunity. Curr Opin Immun 18(6): 656-664, 2006.
Wandstrat AE, Nguyen C, Limaye N, Chan AY, Subramanian S, Tian XH, Yim YS, Pertsemlidis A, Garner HR Jr, Morel L, Wakeland EK: Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus. Immunity. 2004 Dec;21(6):769-80.
Etherton, Mark (2004)
Tabuchi K, Blundell J, Etherton MR, Hammer RE, Liu X, Powell CM, Südhof TC: A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 318(5847): 71-76, 2007.
Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR, Südhof TC: Activity-dependent validation of excitatory vs. inhibitory synapses by Neuroligin-1 vs. Neuroligin-2. Neuron 54(6): 919-931, 2007.
Evers, Bret (2004)
Engelking LJ, Evers BM, Richardson JA, Goldstein JL, Brown MS, Liang G: Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by Iovastatin. J Clin Invest 116(9): 2356-2365, 2006.
Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS: Schoenheimer effect explained - - feedback regulation of cholesterol synthesis in mice mediated by Insig proteins. J Clin Invest 115(9): 2489-2498, 2005.
Gocke, Christian (2001)
Yang M, Culhane JC, Szewczuk LM, Gocke CB, Brautigam CA, Tomchick DR, Machius M, Cole PA, Yu H: Structural basis of histone demethylation by LSD1 revealed by suicide inactivation. Nat Struct Mol Biol 14(6): 535-539, 2007.
Kang J, Gocke CB, Yu H: Phosphorylation-facilitated symoylation of MEF2C negatively regulates its transcriptional activity. BMC Biochem 7:5, 2006.
Gocke CB, Yu H, Kang J: Systematic identification and analysis of mammalian SUMO substrates. J Biol Chem 280(6): 5004-5012, 2005.
Halford, Rebekkah Warren (2002)
Yildiz Y, Matern H, Thompson B, Allegood JC, Warren RL, Ramirez DM, Hammer RE, Hamra FK, Matern S, Russell DW: Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility. J Clin Invest 116(11): 2985-2994, 2006.
Hawasli, Ammar (2002)
Hawasli AH, Benavides DR, Nguyen C, Kansy JW, Hayashi K, Chambon P, Greengard P, Powell CM, Cooper DC, Bibb JA: Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nat Neurosci, 2007 (Epub).
Hawasli AH, Bibb JA: Alternative roles for Cdk5 in learning and synaptic plasticity.
Biotechnol J, 2007 (Epub).
Johnson, Cynthia (2001)
Johnson CL, Owen DM, Gale M Jr: Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense. J Biol Chem 282(14): 10792-10803, 2007.
Saito T, Harai R, Loo YM, Owen DM, Johnson CL, Sinha SC, Akira S, Fujita T, Gale M Jr: Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci USA 104(2): 582-587, 2007.
Chien Y, Kim S, Bumeister R, Loo YM, Kwon SW, Johnson CL, Balakireva MG, Romeo Y, Kopelovich L. Gale M JR, Yeaman C, Camonis JH, Zhao Y, White MA: RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. Cell 127(1):157-70, 2007.
Loo YM, Owen DM, Li K, Erickson AK, Johnson CL, Fish PM, Carney DS, Wang T, Ishida H, Yoneyama M, Fujita T, Saito T, Lee WM, Hagedorn CH, Lau DT, Weinman SA, Lemon SM, Gale M Jr: Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. Proc Natl Acad Sci 103(15): 6001-6006, 2006.
Johnson CL, Gale M Jr: CARD games between virus and host get a new player. Trends Immunol 27(1): 1-4, 2006.
Foy E, Li K, Sumpter R Jr, Loo YM, Johnson CL, Wang C, Fish PM, Yoneyama M, Fujita T, Lemon SM, Gale M Jr: Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proc Natl Acad Sci USA 102(8): 2986-2991, 2005.
Keller, Brian (2001)
Daffis S, Samuel MA, Keller BC, Gale M JR, Diamond MS: Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and –independent mechanisms. PLoS Pathogens 3(7): e106, 2007.
Samuel MA, Whitby K, Keller BC, Marri A, Barchet W, Williams BR, Silverman RH, Gale M Jr, Diamond MS: PKR and RNase L contribute to protection against lethal West Nile virus infection by controlling early viral spread in the periphery and replication in neurons. J Virol 80(14): 7009-7019, 2006.
Keller BC, Fredericksen BL, Samuel AM, Mock RE, Mason PW, Diamond MS, Gale M Jr.: Resistance to alpha/beta interferon is a determinant of West Nile virus replication fitness and virulence. J Virol 80(19): 9424-9434, 2006.
Wang C, Gale M Jr, Keller BC, Huang H, Brown MS, Goldstein JL, Ye J: Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication. Mol Cell 18(4): 425-434, 2005.
Kildebeck, Eric (2005)
Bu D, Tomlinson G, Lewis CM, Zhang C, Kildebeck E, Euhus DM: An intronic polymorphism associated with increased XRCC1 expression, reduced apoptosis and familial breast cancer. Breast Cancer Res Treat 99(3): 257-265, 2006.
Krishnan, Vaishnav (2003)
Berton O, Covington HE 3rd, Ebner K, Tsankova NM, Carle TL, Ulery P, Bohnsle A, Barrot M, Krishnan V, Singewald GM, Singewald N, Birnbaum S, Neve RL, Nestler EJ: Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses. Neuron 55(2): 289-300, 2007.
Roybal K, Theobold D, Graham A, DiNieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P, Takahashi JS, Nestler EJ, Carlezon WA JR, McClung CA: Mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci USA 104(15): 6406-6411, 2007.
Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos CA, Rios M, Monteggia LM, Self DW, Nestler EJ: Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311(5762): 864-868, 2006.
LaPlant, Quincey (2004)
Winstanley CA, LaPlant Q, Theobald DE, Green TA, Bachtell RK, Perrotti LI, DiLeone RJ, Russo SJ, Garth WJ, Self DW, Nestler EJ: DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction. J Neurosci 27(39): 10497-10507, 2007.
Shah S, Lee SF, Tabuchi K, Hao YH, Yu C, LaPlant Q, Ball H, Dann CE 3rd, Sudhof T, Yu G: Nicastrin functions as a gamma-secretase-substrate receptor. Cell 122(3): 435-447, 2005.
Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, LaPlant Q, Sasaki TS, Whistler KN, Neve RL, Self DW, Nestler EJ: Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron 48(2): 303-314, 2005.
Larson, Christopher (2000)
Shulman AI, Larson C, Mangelsdorf DJ, Ranganathan R.
Structural determinants of allosteric ligand activation in RXR heterodimers.
Cell. 2004 Feb 6;116(3):417-29.
McNutt, Markey (2003)
McNutt MC, Lagace TA, Horton JD: Catalytic activity is not required for secreted PCSK9 to reduce LDL receptors in HepG2 cells. J Biol Chem May 2007 (Epub).
Lagace TA, Curtis DE, Garuti R, McNutt MC, Park SW, Prather HB, Anderson NN, Ho YK, Hammer RE, Horton JD: Secreted PCSK9 decreases the number of LDL receptors in heptocytes and in livers of parabiotic mice. J Clin Invest 116(11): 2995-3005, 2006.
Mishra, Prashant (2000)
Mishra P, Socolich M, Wall MA, Graves J, Wang Z, Ranganathan R: Dynamic scaffolding in a G protein-coupled signaling system. Cell 131(1): 80-92, 2007.
Russ WP, Lowery DM, Mishra P, Yaffe MB, Ranganathan R: Natural-like function in artificial WW domains. Nature 437(7058): 579-583, 2005.
Motola, Daniel (2000)
Gerisch B, Rottiers V, Li D, Motola DL, Cummins CL, Lehrach H, Mangelsdorf DJ, Antebi A: A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proc Natl Acad Sci USA 104(12): 5014-5019, 2007.
Rottiers V, Motola DL, Gerisch B, Cummins CL, Nishiwaki K, Mangelsdorf DJ, Antebi A: Hormonal Control of C. elegans Dauer formation and life span by a Rieske-like oxygenase. Dev Cell 10(4): 473-482, 2006.
Motola DL, Cummins CL, Rottiers V, Sharma KK, Li T, Li Y, Suino-Powell K, Xu HE, Auchus RJ, Antebi A, Mangelsdorf DJ: Identification of ligands for DAF-12 that govern Dauer formation and reproduction in C. elegans. Cell 124(6): 1209-1223, 2006.
Ge H, Yang G, Huang L, Motola DL, Pourbahrami T, Li C: Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4. J Biol Chem 279(3): 2038-2045, 2004.
Cheng JB, Motola DL, Mangelsdorf DJ, Russell DW: De-orphanization of cytochrome P450 2R1 - A microsomal vitamin D 25-hydroxylase. J Biol Chem 278(39): 38084-38093, 2003.
Nash, Abigail (2003)
Ko WH, Nash AI, Gardner KH: A LOVely view of blue light photosensing. Nature Chem Biol 3(7): 372-374, 2007.
Nguyen, Baochan (Chan) (2001)
Hawasli AH, Benavides DR, Nguyen C, Kansy JW, Hayashi K, Chambon P, Greengard P, Powell CM, Cooper DC, Bibb JA: Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation. Nat Neurosci May 2007 (Epub).
Nguyen C, Nishi A, Kansy JW, Fernandez J, Hayashi K, Gillardon F, Hemmings HC Jr, Nairn AC, Bibb JA: Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5. J Biol Chem 282(220): 16511-16520, 2007.
Hawasli AH, Benavides DR, Nguyen C, Kansy JW, Chambon P, Greengard P, Powell CM, Cooper DC, Bibb JA: Cdk5 governs learning, memory and synaptic plasticity via NMDA receptors. Submitted to Nature August 2006.
Wei F-Y, Tomizawa K, Ohshima T, Asad A, Saito T, Nguyen C, Bibb JA, Ishiguro K, Kulkarni AB, Pant HC, Mikoshiba K, Matsui H, Hisanaga S: Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability. J Neurochemistry 93: 502-512, 2005.
Kansy JW, Daubner SC, Nishi A, Sotogaku N, Lloyd MD, Nguyen C, Lu L, Haycock JW, Hope BT, Fitzpatrick PF, Bibb JA: Identification of tyrosine hydroxylase as a physiological substrate for Cdk5. J Neurochem 91(2): 374-384, 2004.
Nguyen C, Bibb JA: Cdk5 and the mystery of synaptic vesicle endocytosis. J Cell Biol 163(4): 697-699, 2003.
Orvedahl, Anthony (2004)
He C, Orvedahl A: 2007 Keystone Symposium on Autophagy in Health and Disease. Autophagy 3(5): 527-536, 2007.
Orvedahl A, Alexander D, Tallóczy Z, Sun Q, Wei Y, Zhang W, Burns D, Leib DA, Levine B: HSV-1 ICP34.5 confers neurovirulence by targeting the beclin 1 autophagy protein. Cell Host & Microbe 1(1): 23-35, 2007.
Owen, David (2003)
Huang H, Sun F, Owen DM, Li W, Chen Y, Gale M Jr, Ye J: Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc Natl Acad Sci USA 104(14): 5848-5853, 2007.
Johnson CL, Owen DM, Gale M Jr: Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense. J Biol Chem 282(14): 10792-10803, 2007.
Saito T, Harai R, Loo YM, Owen DM, Johnson CL, Sinha SC, Akira S, Fujita T, Gale M Jr: Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci USA 104(2): 582-587, 2007.
Loo YM, Owen DM, Li K, Erickson AK, Johnson CL, Fish PM, Carney DS, Wang T, Ishida H, Yoneyama M, Fujita T, Saito T, Lee WM, Hagedorn CH, Lau DT, Weinman SA, Lemon SM, Gale M Jr: Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. Proc Natl Acad Sci 103(15): 6001-6006, 2006.
Park, Joseph (2001)
Maines JZ, Park JK, Williams M, McKearin DM: Stonewalling Drosophila stem cell differentiation by epigenetic controls. Development 134(8): 1471-1479, 2007.
Park JK, Liu X, Strauss TJ, McKearin DM, Liu Q: The miRNA pathway intrinsically controls self-renewal of drosophila germline stem cells. Curr Biol 17(6): 533-538, 2007.
Paulson, Vera (2005)
Jackson SR, Zhu CH, Paulson V, Watkins L, Dikmen ZG, Gryaznov SM, Wright WE, Shay JW: Antiadhesive effects of GRN163L – an oligonucleotide N3’->P5’ thio-phosphoramidate targeting telomerase. Cancer Res 67(3): 1121-1129, 2007.
Poole, Alan (2002)
Poole AM, Ranganathan R: Knowledge-based potentials in protein design. Curr Opin Struct Biol 16(4): 508-513, 2006.
Rasar Young, Melissa (2001)
Rasar MA, Hammes SR: The physiology of the Xenopus laevis ovary. Meth Molec Biol 322:17-30, 2006.
Rasar M, DeFranco DB, Hammes SR: Paxillin regulates steroid-triggered meiotic resumption in oocytes by enhancing an all-or-none positive feedback kinase loop. J Biol Chem 281(51); 39455-39464, 2006.
Haas D, White SN, Lutz LB, Rasar M, Hammes SR: The modulator of nongenomic actions of the estrogen receptor (MNAR) regulates transcription-independent androgen receptor-mediated signaling: evidence that MNAR participates in G protein-regulated meiosis in Xenopus laevis oocytes. Mol Endocrinol 19(8): 2035-2046, 2005.
Renthal, Nora Edwards (2004)
Russo SJ, Bolanos CA, Theobald DE, Decarolis N, Renthal W, Kumar A, Winstanley CA, Renthal NE, Wiley MD, Self DW, Russell DS, Neve RL, Eisch AJ, Nestler EJ: IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nature Neurosci 10: 93-99, 2006.
Renthal, William (2003)
Tsankova NM, Renthal W, Kumar A, Nestler EJ: Epigenetic regulation in psychiatric disorders. Nat Rev Neurosci 8(5): 355-367, 2007.
Russo SJ, Bolanos CA, Theobald DE, Decarolis N, Renthal W, Kumar A, Winstanley CA, Renthal NE, Wiley MD, Self DW, Russell DS, Neve RL, Eisch AJ, Nestler EJ: IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nature Neurosci 10: 93-99, 2006.
Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ: Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 9(4): 519-525, 2006.
Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos CA, Rios M, Monteggia LM, Self DW, Nestler EJ: Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311(5762): 864-868, 2006.
Colvis CM, Pollock JD, Goodman RH, Impey S, Dunn J, Mandel G, Champagne FA, Mayford M, Korzus E, Kumar A, Renthal W, Theobald DE, Nestler EJ: Epigenetic mechanisms and gene networks in the nervous system. J Neurosci 25(45): 10379-10389, 2005.
Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, LaPlant Q, Sasaki TS, Whistler KN, Neve RL, Self DW, Nestler EJ: Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron 48(2): 303-314, 2005.
Willie JT, Renthal W, Chemelli RM, Miller MS, Scammell TE, Yanagisawa M, Sinton CM: Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates. Neuroscience 130(4): 983-995, 2005.
Reuter, Anne (2002)
Reuter AL, Goji K, Bingham NC, Matsuo M, Parker KL: A novel mutation in the accessory DNA-binding domain of human steroidogenic factor 1 causes XY gonadal dysgenesis without adrenal insufficiency. Europ J Endocrin 157(2): 233-238, 2007.
Sahin, Bogachan (1998)
Sahin B, Galdi S, Hendrick J, Greene RW, Snyder GL, Bibb JA: Evaluation of neuronal phosphoproteins as effectors of caffeine and mediators of striatal adenosine A2A receptor signaling. Brain Res 1129(1): 1-14, 2007.
Sahin B, Shu H, Fernandez J, El-Armouche A, Molkentin JD, Nairn AC, Bibb JA: Phosphorylation of protein phosphatase inhibitor-1 by protein kinase C. J Biol Chem 281(34): 24322-24335, 2006.
Sahin B, Kansy JW, Nairn AC, Spychala J, Ealick SE, Fienberg AA, Greene RW, Bibb JA: Molecular characterization of recombinant mouse adenosine kinase and evaluation as a target for protein phosphorylation. Eur J Biochem 271(17): 3547-3555, 2004.
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD: PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med 10(3): 248-254, 2004.
Sahin B, Bibb JA: Protein kinases talk to lipid phosphatases at the synapse. Proc Natl Acad Sci USA 101(5): 1112-1113, Epub 2004.
Schmidt, Daniel (2003)
Moore DD, Kato S, Xie W, Mangelsdorf DJ, Schmidt DR, Xiao R, Kliewer SA: International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D receptor. Pharmacol Rev 58(4): 742-759, 2006.
Smith, Christopher (2005)
Anderson RC, Pickett EA, Smith CL, Kiyozumi D, Kiyotoshi S, Tallquist MD: Alteration of matrix maintenance in PDGF receptor deficient embryonic dermis (Submitted to J Invest Derm, 2007).
Tannous, Paul (2001)
Zhu H, Tannous P, Johnstone JL, Kon Y, Shelton JM, Richardson JA, Le V, Levine B, Rothermel BA, Hill JA: Cardiac authophagy is a maladaptive response to hemodynamic stress. J Clin Invest 117(7): 1782-1793, 2007.
Kong Y, Tannous P, Lu G, Berenji K, Rothermel BA, Olson EN, Hill JA: Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation 113(22): 2579-2588, 2006.
Richardson KE, Tannous P, Berenji K, Nolan B, Bayless KH, Davis GE, Rothermel BA, Hill JA: Guanosine triphosphatase activation occurs downstream of calcineurin in cardiac hypertrophy. J Investig Med 53(8): 414-424, 2005.
Rothermel BA, Berenji K, Tannous P, Kutschke W, Dey A, Nolan B, Yoo KD, Demetroulis E, Gimbel M, Cabuay B, Karimi M, Hill JA: Differential activation of stress-response signaling in load-induced cardiac hypertrophy and failure. Physiol Genomics 23(1): 18-27, 2005.
Tsankova, Nadejda (2000)
Berton O, Covington HE 3rd, Ebner K, Tsankova NM, Carle TL, Ulery P, Bohnsle A, Barrot M, Krishnan V, Singewald GM, Singewald N, Birnbaum S, Neve RL, Nestler EJ: Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses. Neuron 55(2): 289-300, 2007.
Tsankova NM, Renthal W, Kumar A, Nestler EJ: Epigenetic regulation in psychiatric disorders. Nat Rev Neurosci 8(5): 355-367, 2007.
Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ: Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 9(4): 519-525, 2006.
Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos CA, Rios M, Monteggia LM, Self DW, Nestler EJ: Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311(5762): 864-868, 2006.
Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, LaPlant Q, Sasaki TS, Whistler KN, Neve RL, Self DW, Nestler EJ: Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron 48(2): 303-314, 2005.
Tsankova NM, Kumar A, Nestler EJ: Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci 24(24): 5603-5610, 2004.
Tuckerman, Jason (2003)
Sousa EH, Tuckerman JR, Gonzalez G, Gilles-Gonzalez MA: DosT and DevS are oxygen-switched kinases in Mycobacterium tuberculosis. Protein Science 16(8): 1708-1719, 2007.
Sousa EH, Tuckerman JR, Gonzalez G, Gilles-Gonzalez MA: A memory of oxygen binding explains the dose response of the heme-based sensor FixL. Biochemistry 46(21): 6249-57, 2007.
Dunham CM, Dioum EM, Tuckerman JR, Gonzalez G, Scott WG, Gilles-Gonzalez MA: A distal arginine in oxygen-sensing Heme-PAS domains is essential to ligand binding, signal transduction, and structure. Biochem 42(25): 7701-7708, 2003.
Valasek, Mark (2002)
Valasek MA, Repa JJ: The power of real-time PCR. Adv Physiol Educ 29(3); 151-159, 2005.
Valasek MA, Weng J, Shaul PW, Anderson RG, Repa JJ: Caveolin-1 is not required for murine intestinal cholesterol transport. J Biol Chem 280(3): 28103-28109, 2005.
Li H, Repa JJ, Valasek MA, Beltroy EP, Turley SD, German DC, Dietschy JM: Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease. J Neuropathol Exp Neurol 64(4): 323-333, 2005.
Xiong Y, Miyamoto N, Shibata K, Valasek MA, Motoike T. Kedzierski RM, Yanagisawa M: Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci USA 101(4): 1045-1050, 2004.
Wang, Andrew (2004)
Subramanian S, Tus K, Li QZ, Wang A, Tian XH, Zhou J, Liang C, Bartov G, McDaniel LD, Zhou XJ, Schultz RA, Wakeland EK: A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc Natl Acad Sci USA 103(26): 9970-9975, 2006.
Ward, Brant (2000)
Ward BR, Jester JV, Nishibu A, Vishwanath M, Shalhevet D, Kumamoto T, Petroll WM, Cavanagh HD, Takashima A: Local thermal injury elicits immediate dynamic behavioral responses by corneal Langerhans cells. Immunology 120(4): 556-572, 2007.
Nishibu A, Ward BR, Boes M, Takashima A: Roles of IL-1 and TNFalpha in dynamic behavioral responses of Langerhans cells to topical hapten application. J Dermatol Sci 45(1): 23-30, 2006.
Vishwanath M, Nishibu A, Saeland S, Ward BR, Mizumoto N, Ploegh HL, Boes M, Takashima A: Development of intravital intermittent confocal imaging system for studying Langerhans cell turnover. J Invest Dermatol 126(11):2452-2457, 2006.
Nishibu A, Ward BR, Jester JV, Ploegh HL, Boes M, Takashima A: Behavioral responses of epidermal Langerhans cells in situ to local pathological stimuli. J Invest Dermatol 126(4): 787-796, 2006.
Jester JV, Ward BR, Takashima A, Gatlin J, Garcia JV, Cavanagh HD, Petroll WM: Four-dimensional multiphoton confocal microscopy: the new frontier in cellular imaging. Ocul Surf 2(1): 10-20, 2004.
Kumamoto T, Shalhevet D, Matsue H, Mummert ME, Ward BR, Jester JV, Takashima A: Hair follicles serve as local reservoirs of skin mast cell precursors. Blood 102(5): 1654-1660, Epub 2003.
Wedin, Kyle (2002)
Lenertz LY, Lee BH, Min X, Xu BE, Wedin K, Earnest S, Goldsmith EJ, Cobb MH: Properties of WNK1 and implications for other family members. J Biol Chem 280(29): 26653-26658, 2005.
Wilkinson, Matthew (2005)
Carle TL, Ohnishi YN, Ohnishi YH, Alibhai IN, Wilkinson MB, Kumar A, Nestler EJ: Proteasome-dependent and –independent mechanisms for FosB destabilization: identification of FosB degron domains and implications for DeltaFosB stability. Europ J Neurosci 25(10): 3009-3019, 2007.
Young, Bryan (2001)
Chang S, Young BD, Li S, Qi X, Richardson JA, and Olson EN: Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell. 2006 July 28;126(2):321-34.
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