DALLAS - Aug. 18, 2005 - Researchers at UT Southwestern Medical Center are seeking patients to participate in medical studies on dietary or medication control of type 2 diabetes, comparisons of two fatty acids and sinus problems related to acid reflux. All clinical trials are approved by UT Southwestern's Institutional Review Board, which reviews them for benefits, risks, side effects and informed consent.

Type 2 diabetes
UT Southwestern Medical Center researchers are seeking patients with documented histories of type 2 diabetes controlled solely with diet or oral medications for a four-night inpatient metabolic evaluation. Study participants must be 35 years of age and older and have no history of cardiovascular, renal or liver disease. Patients must also not be on medications for high cholesterol or anti-inflammatory drugs. For more information, please call 214-648-0439.

Two dietary fats
Volunteers are needed to participate in a UT Southwestern Medical Center trial that compares two kinds of fats, medium-chain and long-chain fatty acids. Researchers are attempting to determine which fat is better and the study involves two clinic visits lasting about 10 hours each. Some compensation is offered for participating in the study. To qualify, you should be either a healthy adult or a person who is moderately overweight and tends to have metabolic complications such as moderate elevation of blood fats or sugar or both. Those interested in additional study details should call 214-648-2419.

Acid reflux
Researchers at UT Southwestern Medical Center are looking for study participants to determine whether some sinus problems may be related to acid reflux. Researchers suspect some sinus-related problems in people without allergies may be due to acid traveling from the stomach to the larynx and into the nasal passages. The study seeks non-allergic patients who suffer from nasal congestion, post-nasal drip, runny nose or scratchy throat. Participants must be between 18 and 80, not pregnant or breast feeding. Partici-pants will get esomeprazole (the generic form of Nexium) for eight weeks, nothing for two weeks and a placebo for eight weeks in the 18-week study. Patients must be available to come to UT Southwestern for at least six visits and fill out a diary at home. Compensation is available. Call 214-648-7602 for information.

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Media Contact: Katherine Morales
214-648-3404
e-mail: katherine.morales@utsouthwestern.edu

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