The impact of nutrition therapy on wound healing for people suffering from severe malnutrition or specific metabolic deficiencies is well known. However, effects of supplementing nutrients on soft tissue wound healing in otherwise normal, healthy adults is an area of clinical importance, but little information is available. Proteolytic enzymes and other biological materials have been reported to moderate the inflammatory cycle and up-regulate the healing process. Medical claims from many oral supplements are marketed for surgical patients to decrease edema, bruising and discomfort.  However, a randomized, placebo-controlled, cross-over clinical trial in healthy adults to examine the effects of oral nutritional supplements on soft tissue healing times has not been reported, to the best of our knowledge. The goal of these studies are to perform clinical trials to scientifically evaluate the effectiveness of an oral supplement on soft tissue wound healing.