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2005 Clinical Research Scholars Bios and Projects
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The 2005 Clinical Research Scholars and their research interests are:

Cindy Darnell Cindy Bowens, M.D., Assistant Professor in Pediatrics, earned her medical degree from the University of Louisville School of Medicine. Her research areas include the management of pain and sedation of critically ill children. She will focus on pain management in pediatrics and opioid tolerance. Her research interests revolve around the appropriate application of analgesic/sedative agents in Pediatric ICU patients, methods of monitoring pain and sedation, as well as finding better methods to combat tolerance, physical dependence and withdrawal in Pediatric ICU patients who require prolonged medication exposure.
Alice Chang Alice Chang, M.D., an Instructor in Internal Medicine, earned her medical degree from Yale University School of Medicine. Her research interests center on gender differences in cardiovascular disease. She will focus on the influence of testosterone on cardiovascular disease in women with Polycystic Ovarian Syndrome.
Randall Friese Randall Friese, M.D., Assistant Professor in Surgery, earned his medical degree from the University of Maryland School of Medicine. Currently he is interested in the effects of sleep deprivation on recovery from critical illness and injury. Although the effects of sleep deprivation on immunity and well-being of normal subjects is frequently studied, the effects of sleep deprivation in patients recovering from critical illness are not well quantified.
Subroto Ghose Subroto Ghose, M.D., Ph.D., Assistant Professor in Psychiatry, earned his M.D. degree from Maulana Azad Medical College, New Delhi, India, followed by his Ph.D. in biology from Georgetown University. His interests include the etiology and pathophysiology of schizophrenia, including the study of genetic predisposition and what role gene-environment interactions may play.
Rebeca Gracia Rebeca Gracia, Pharm.D., Clinical Instructor of Emergency Medicine, earned her Pharm.D. from Texas Tech University School of Pharmacy. She will focus on the neurobehavioral effects of sub-acute pesticide exposure in children and adolescence. Dr. Gracia will aim to clarify a "safe" exposure level for pesticides by working with research team representative from neurology, epidemiology, toxicology and pediatrics to define the toxic syndrome associated with low level exposures, identify susceptible populations, and suggest methods to reduce risk as a public health intervention.
Heidi Jacobe Heidi Jacobe, M.D., Assistant Professor in Dermatology, earned her medical degree from Baylor College of Medicine. Her areas of interest include the genetics of psoriasis and ultraviolet light therapy for skin disease.
Janna Journeycake Janna Journeycake, M.D., Assistant Professor in Pediatrics, received her medical degree from the University of Oklahoma College of Medicine. Her research interest is thromboembolic conditions in children, and she currently is focusing on the acute and long-term effects of the common problem of catheter-related thrombosis.
Ildiko Lingvay Ildiko Lingvay, M.D., M.P.H., Assistant Professor in Internal Medicine, earned her medical degree from Carol Davila University of Medicine and Pharmacy in Bucharest, Romania. Her research focuses on novel approaches to the evaluation of beta-cell function and on interventions to improve beta-cell function in non-insulin-dependent diabetics.
Charles Quinn Charles Quinn, M.D., Assistant Professor in Pediatrics, earned his medical degree from UT Southwestern. His proposed research comprises complementary mechanistic and therapeutic investigations, both short- and long-term, designed to understand the causes of sickle cell pain and determine how best to treat it.
Carlos Timaran Carlos Timaran, M.D., Assistant Professor in Surgery, earned his medical degree from the University of Cauca in Colombia. His research focuses on ethnic differences in the prevalence of peripheral arterial disease, as well as the risk factors, treatment and outcomes of patients with vascular diseases, with the long term hope to provide the basis to improve the existing health care gap and disparity in cardiovascular health among minorities.
Jane Wigginton Jane Wigginton, M.D., Assistant Professor in Surgery/Emergency Medicine, received her medical degree from UT Southwestern. Her research areas include gender-related differences and oxidant injury in resuscitation and in cardiac arrest, and research into the use of sex steroids as acute resuscitation drugs.