Forest (Now Enrolling!)
To compare safety and efficacy between escitalopram and Duloxetine in outpatients with MDD, that partially respond to 2 weeks of escitalopram 10 mg.
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DVS (Now Enrolling!)
An 8-wk, multicenter, randomized, double blind study to evaluate the efficacy, safety, and tolerability of desvenlafaxine SR (DVS-SR) versus escitalopram in postmenopausal women with MDD.
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Takeda Insomnia (Now Enrolling!)
To assess the effects of ramelteon, used in combination with a selective serotonin reuptake inhibitor (SSRI) antidepressant (escitalopram), in advancing time to remission of depressive symptoms and accompanying resolution of insomnia.
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Duloxetine (Now Enrolling!)
To assess the effect of duloxetine treatment on cognitive function, symptom severity, and psychosocial function in persons with major depressive disorder.
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Abilify for Cogntive Dysfunction (Now Enrolling!)
To explore alternative treatments for individuals with MDD experiencing cognitive disfunction.
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Implementation of Algorithms for Computerized Treatments of Depression (IMPACTS)
To evaluate the effectiveness of a computerized decision support system for depression (CDSS-D) in enhancing the quality of patient care.
Texas Implementation of Medication Algorithms (TIMA)
To develop and continuously update medication algorithms and to train systems to utilize them in order to reduce the immediate and long-term emotional, physical and financial burdens of mental disorders for clients, their families, and their health care systems.