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EDUCATION/TRAINING
| Institution and Location |
Degree
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Years
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Field
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| Guys Hospital Medical School, University of London, U.K. |
Ph.D.
|
1991
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Biochemistry
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| University of London, U.K. |
B.S.
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1982
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Biochemistry
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RESEARCH AND PROFESSIONAL EXPERIENCE
| 1982 - 1988 |
|
Research Technician, Department of Molecular Biology, Burroughs-Welcome Research Laboratories, Beckenham, Kent, U.K. |
| 1991 - 1994 |
|
Postdoctoral Fellow, Hughes Medical Institute, University of Texas Southwestern Medical Center at Dallas (Lab of Drs. Mary-Jane Gething and Joseph Sambrook) |
| 1994 - 2000 |
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Postdoctoral Fellow, Hughes Medical Institute, University of Texas Southwestern Medical Center at Dallas (Lab of Dr. Robert Hammer) |
| 2000 - Present |
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Instructor, Hughes Medical Institute, University of Texas Southwestern Medical Center at Dallas (Lab of Dr. Robert Hammer) |
PUBLICATIONS
Comerford SA, Clouthier DE, Hinnant EA, Hammer RE. Induction of hepatocyte proliferation and death by modulation of T-Antigen expression. Oncogene. 2003 Apr 24;22(16):2515-30.
Hammer RE, Comerford SA. Glomerulosclerosis, tubulointerstitial fibrosis and obstructive uropathy in PEPCK-TGF-b1. Am J Kidney Diseases. 1999. 34:177-183.
Clouthier DE, Comerford SA, Hammer RE. Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-b1 transgenic mice. J Clin Invest. 1997 Dec 1;100(11):2697-713.
Alizadeh H, Ma D, Berman M, Bellingham D, Comerford SA, Gething MJ, Sambrook JF, Niederkorn JY. Tissue-type plasminogen activator-induced invasion and metastasis of murine melanomas. Curr Eye Res. 1995 Jun;14(6):449-58.
Comerford SA, Maika SD, Laimins LA, Messing A, Elsasser HP, Hammer RE. E6 and E7 expression from the HPV 18 LCR: development of genital hyperplasia and neoplasia in transgenic mice. Oncogene. 1995 Feb 2;10(3):587-97.
Romanos MA, Hughes FJ, Comerford SA, Scorer CA. Production of a phosphorylated GST::HPV-6 E7 fusion protein using a yeast expression vector and glutathione S-transferase fusions. Gene. 1995 Jan 11;152(1):137-8.
Anand R, Ma D, Alizadeh H, Comerford SA, Sambrook JF, Gething MJ, McLean IW, Niederkorn JY. Characterization of intraocular tumors arising in transgenic mice. Invest Ophthalmol Vis Sci. 1994 Aug;35(9):3533-9.
Ma D, Comerford S, Bellingham D, Sambrook J, Gething MJ, Alizadeh H, Anand R, Mellon J, Niederkorn JY. Capacity of simian virus 40 T antigen to induce self-tolerance but not immunological privilege in the anterior chamber of the eye. Transplantation. 1994 Mar 15;57(5):718-25.
Ma D, Alizadeh H, Comerford SA, Gething MJ, Sambrook JF, Anand R, Niederkorn JY. Rejection of intraocular tumors from transgenic mice by tumor-infiltrating lymphocytes. Curr Eye Res. 1994 May;13(5):361-9.
Shepherd PS, Tran TT, Rowe AJ, Cridland JC, Comerford SA, Chapman MG, Rayfield LS. T cell responses to the human papillomavirus type 16 E7 protein in mice of different haplotypes. J Gen Virol. 1992 May;73 ( Pt 5):1269-74.
Comerford SA, McCance DJ, Dougan G, Tite JP. Identification of T- and B-cell epitopes of the E7 protein of human papillomavirus type 16. J Virol. 1991 Sep;65(9):4681-90.
Kahl LP, Byram JE, David JR, Comerford SA, Von Lichtenberg F. Leishmania (Viannia) braziliensis: comparative pathology of golden hamsters infected with isolates from cutaneous and mucosal lesions of patients residing in Tres Bracos, Bahia, Brazil. Am J Trop Med Hyg. 1991 Feb;44(2):218-32.
Dougan G, Chatfield S, Roberts M, Charles I, Comerford S, Li LJ, Fairweather N. Bacterial pathogens--a route to oral drug delivery. Biochem Soc Trans. 1990 Oct;18(5):746-8. Review. No abstract available.
Fairweather NF, Chatfield SN, Charles IG, Roberts M, Lipscombe M, Li LJ, Strugnell D, Comerford S, Tite J, Dougan G. Use of live attenuated bacteria to stimulate immunity. Res Microbiol. 1990 Sep-Oct;141(7-8):769-73. Review.
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