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We cannot detail all of the medications available to treat hypertension, nor do we wish to second-guess your doctor's decisions regarding the medications prescribed to you. For information purposes only, we can touch on the most common medications and their general affects. For more detailed information on drug interactions or possible side effects, contact your doctor, pharmacist, or the drug manufacturer.

There are 3 main types of antihypertensive drugs. Each type lowers blood pressure in different ways. More than 60 different drugs are currently available to treat hypertension. Within each category, there are multiple individual classes of medications.

Diuretics--Reduce the amount of fluid within the blood vessels by increasing the excretion of water and salt through the kidneys

Thiazides, the most popular being hydrochlorothiazide

Furosemide and bumetamide

Indapamide

Sympathetic Nervous Inhibitors--Slow the heart

Guanfacine

Alpha-blockers (relax blood vessels)

Doxazosin, terazosin

Beta-blockers (slow the heart and reduce the force of its contractions)

Atenolol, metoprolol, propranolol, and about 8 others

Vasodilators--Open the blood vessels and allow the arteries to expand

Hydralazine and Minoxidil

Angiotensin-converting enzyme inhibitors (ACEIs) (relax blood vessels)

Captopril, enalapril, lisinopril, quinapril, ramipril, and others

Angiotensin II-receptor blockers (ARBs) (relax blood vessels)

Candesartan, irbesartan, losartan, and others

Calcium-channel blockers (CCBs) (relax blood vessels)

Amlodipine, diltiazem, nifedipine, verapamil, and others

 

Diuretics

Adrenergic Inhibitors

Vasodilators

Thiazides

     Chlorthalidone

     Indapamide

     Metolazone

     Thiazides

Loop diuretics

     Bumetanide

     Ethacrynic acid

     Furosemide

     Torsemide

Potassium sparers

     Amiloride

     Spironolactone

     Triamterene

 

Peripheral inhibitors

     Guanadrel

     Guanethidine

     Reserpine         

Central a2-agonists

     Clonidine

     Guanabenz

     Guanfacine

     Methyldopa

a1-blockers

     Dozazosin

     Prazosin

     Terazosin

 

b-blockers

     Acebutolol

     Atenolol

     Betaxolol

     Bisoprolol

     Carteolol

     Metoprolol

     Nadolol

     Penbutolol

     Pindolol

     Propranolol

     Timolol

Combined a-, b-blockers

     Carvediol

     Labetalol           

Direct

     Hydralazine

     Minoxidil

Calcium channel blockers

     Dihydropyridines

         Amlodipine

         Felodipine

         Isradipine

         Nicardipine

         Nifedipine

         Nisoldipine

     Diltiazem

     Verapamil

   

ACE inhibitors

     Benazepril

     Captopril

     Enalapril

     Fosinopril

     Lisinopril

     Moexipril

     Quinapril

     Perindopril

     Ramipril

     Trandolapril

A-II receptor blockers

     Candesartan

     Eprosartan

     Irbesartan

     Losartan

     Telmisartan

     Valsartan

Most patients with high blood pressure will need more than one drug to bring their blood pressure to below 140/90. Combinations of various drugs in one tablet are available.

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