This course consists of lectures and small-group laboratory sessions. It is offered by Neurology and Neuropathology with assistance from the departments and/or divisions of Cell Biology, Physiology, Psychiatry, Anesthesiology and Pain Management, Neuroradiology, and the Center for Basic Neuroscience. Basic concepts in anatomy, cellular physiology and neural-systems physiology are covered in the course. Emphasis is given to the practical application of these basic anatomical and physiological priniciples to human neuroscience and neuropathology.

This course examines the physiological function and regulation of major organ systems of the human body and their components. Topics include membranes and transport mechanisms; skeletal, cardiac and smooth muscle; and the cardiovascular, respiratory, renal and gastrointestinal systems. Instruction consists of lectures, problem-solving and case-study sessions, and clinical correlations. The course not only emphasizes mechanistic and integrative functions of normal physiology but also introduces and explores abnormal function that occurs in many human diseases.