Frank-Cannon TC, TA Tran, KA Ruhn, TN Martinez, M Marvin, J Hong, M Hartley, I Treviño, B Casey, MS Goldberg and MG Tansey (2008) Parkin deficiency increases vulnerability to inflammation-related nigral degeneration. J Neurosci, in press.
McCoy MK, KA Ruhn, TN Martinez, FE McAlpine, A Blesch and MG Tansey (2008) Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats. Molecular Therapy 16(9):1572-9
Lee JK, MK McCoy, AS Harms, KA Ruhn, SJ Gold and MG Tansey (2008) Regulator of G-protein signaling-10 (RGS10) promotes dopaminergic neuron survival via regulation of the microglial inflammatory response. J Neurosci 28(34):8517-28
Tran TA*, MK McCoy*, MB Sporn and MG Tansey (2008) The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection. Journal of Neuroinflammation 5:14
McCoy MK*, TN Martinez*, KA Ruhn, PC Wrage, EW Keefer, BR Botterman, KE Tansey and MG Tansey (2008) Autologous transplants of Adipose-Derived Adult Stromal (ADAS) cells afford dopaminergic neuroprotection in a model of Parkinson's disease. Experimental Neurology 210(1):14-29
Wrage PC, TA Tran, K To, EW Keefer, KA Ruhn, J Hong, S Hattangadi, I Treviño and MG Tansey (2008) The neuro-glial properties of adipose-derived adult stromal (ADAS) cells are not regulated by Notch 1 and are not derived from neural crest lineage. PLoS ONE 3(1): e1453
Repa JJ, H Li, TC Frank-Cannon, MA Valasek, SD Turley, MG Tansey and JM Dietschy (2007) Liver X Receptor Activation Enhances Cholesterol Loss from the Brain, Decreases Neuroinflammation, and Increases Survival of the NPC1 Mouse. J Neurosci 27(52):14470-80
McCoy MK, TN Martinez, KA Ruhn, DE Szymkowski, CG Smith, BR Botterman, KE Tansey and MG Tansey (2006) Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease. J Neurosci 26(37):9365-75
Yang X, T Tomita, M Wines-Samuelson, V Beglopoulos, MG Tansey, R Kopan and J Shen (2006) Notch1 signaling influences v2 interneuron and motor neuron development in the spinal cord. Dev Neurosci 28:102-17
Steed* PM, MG Tansey*, J Zalevsky*, et al. and BI Dahiyat (2003) Inactivation of TNF signaling using rationally designed dominant-negative TNF variants. Science 301:1895-98
Cheng H-T, JH Miner, MH Lin, MG Tansey, K Roth and R Kopan (2003) Gamma-secretase activity is dispensable for the mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney. Development 130:5031-42
Encinas* M, MG Tansey*, BA Tsui-Pierchala, JX Comella, J Milbrandt and EM Johnson (2001) cSrc is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphathidylinositol-3 kinase (PI-3K)-dependent pathway. J Neurosci 21:1464-72
Tansey* MG, RH Baloh*, J Milbrandt and EM Johnson (2000) GFRa-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation and neuronal survival. Neuron 25:611-23
Baloh RH, MG Tansey, EM Johnson and J Milbrandt (2000) Functional mapping of receptor-specificity domains of glial cell line-derived neurotrophic factor (GDNF) family ligands and production of GFRa1/RET-specific agonists. J Biol Chem 275:3412-20
Baloh RH, MG Tansey, PA Lampe, TJ Fahrner, H Enomoto, KS Simburger, ML Leitner, T Araki, EM Johnson and J Milbrandt (1998) Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRa3-RET receptor complex. Neuron 21:1291-302
*Authors contributed equally
Page Maintained by: The Department of Physiology
Last reviewed: October 18, 2008
