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| Test Description |
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Test Name
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Antiprothrombin Antibodies (IgG, IgM) |
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Synonym(s)
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Description
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Antiphospholipid antibodies are a heterogenous group of immunoglobulins that bind to several anionic phospholipids, to phospholipids-protein complexes, and to certain proteins (cofactors) in the absence of anionic phospholipids. Antibodies to other protein cofactors (Prothrombin) have been reported in patients with the antiphospholipid syndrome (APS). Elevated serum levels of these antibodies are associated with an increased risk for APS, characterized by recurrent arterial or venous thrombosis, thrombocytopenia, and/or fetal loss. An ELISA assay is utilized to detect antibodies directed against Prothrombin in the patient's serum. These antibodies may be IgG and IgM. |
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Methodology
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ELISA |
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Performed
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Friday |
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Turnaround Time
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1-7 days |
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Specimen Requirements
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5 mL serum (red top or SST tube)
Separate from cells as soon as possible and freeze serum immediately.
Transport frozen.
Minimum volume 2 mL. |
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Rejection Criteria
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Serum hemolyzed, icteric, or lipemic. |
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CPT Code(s)
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86147 x 2 |
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Reference Range
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IgG ≤ 7 GPS
IgM ≤ 15 MPS
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Contact Information
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Hemostasis Lab: 214-645-5067
Customer Service: 214-645-7057, Toll Free 877-887-8136 |
Last Modified: 02/22/2011 |
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