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| Test Description |
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Test Name
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Antiphosphatidylserine Antibodies (IgG, IgM, IgA) |
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Synonym(s)
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Description
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Antiphosphatidylserine antibodies are part of antiphospholipid antibody syndrome and are associated with recurrent thrombosis, both venous and arterial, and recurrent fetal loss. An ELISA assay detects them. Unlike cardiolipin, phosphatidylserine is a more physiologically relevant phospholipid due to its presence in cell membranes of endothelial cells and platelets and its role in the coagulation cascade. Patients with positive reactions to both cardiolipin and phosphatidylserine antibodies can appear transiently at low levels during many infections. If a patient first tests positive while there are clinical signs of infection, the test should be repeated after an interval of six months. |
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Methodology
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ELISA |
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Performed
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Tuesday |
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Turnaround Time
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1-5 days |
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Specimen Requirements
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5 mL serum (red top or SST tube)
Separate from cells as soon as possible and freeze serum immediately.
Transport frozen.
Minimum volume 2 mL. |
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Rejection Criteria
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Serum hemolyzed, icteric, or lipemic. |
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CPT Code(s)
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86148 x 3 |
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Reference Range
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IgG ≤9 GPS (IgG anti-phosphatidylserine units)
IgM≤13 MPS (IgM anti-phospatidylserine units)
IgA≤8 APS (IgG anti-phospatidylserine units)
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Contact Information
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Hemostasis Lab: 214-645-5067
Customer Service: 214-645-7057, Toll Free 877-887-8136 |
Last Modified: March 12, 2008 |
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