|
 |
|
| Test Description |
|
Test Name
|
Anticardiolipin Antibodies (IgG, IgM, IgA) |
|
Synonym(s)
|
ACLA, Cardiolipin Antibodies |
|
Description
|
Antiphospholipid antibodies are associated with recurrent thrombosing both venous and arterial, and recurrent fetal loss. They are very heterogeneous, detected by clotting assays (often called lupus anticoagulants) or immunologic assays. Cardiolipin is a negatively charged phospholipid which is used in an ELISA Assay to detect antibodies in the patient's serum. These antibodies may be IgG, IgM, and/or IgA. When testing for phospholipid antibodies, both the lupus anticoagulants test and cardiolipin antibodies should be ordered since patients can have either or both antibodies. Patients with current or prior syphillis infections may have a positive anticardiolipin antibody test. Transient anticardiolipin antibodies can be seen with infections. Recommend repeat study in 4 - 6 months. |
|
Methodology
|
ELISA |
|
Performed
|
Monday, Thursday |
|
Turnaround Time
|
1-5 days |
|
Specimen Requirements
|
5 mL serum (red top or SST tube)
Separate from cells as soon as possible and freeze serum immediately.
Transport frozen.
Minimum volume 2 mL. |
|
Rejection Criteria
|
Serum hemolyzed, icteric, or lipemic. |
|
CPT Code(s)
|
86147 x 3 |
|
Reference Range
|
IgG ≤13 GPL
IgM ≤ 9 MPL
IgA ≤ 16 APL
|
|
Contact Information
|
Hemostasis Lab: 214-645-5067
Customer Service: 214-645-7057, Toll Free 877-887-8136 |
Last Modified: 01/05/2011 |
|
