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| Test Description |
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Test Name
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Anti-Beta 2 Glycoprotein 1 Antibodies (IgG, IgM, IgA) |
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Synonym
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Anti-B2-Glycoprotein 1 |
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Description
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Beta-2 Glycoprotein 1 is an anticoagulant protein normally found in serum. Recent studies have demonstrated that some antiphospholipid antibodies require this protein as cofactor for optimal in-vitro binding and that some antiphospholipid antibodies may recognize the Beta-2 Glycoprotein 1 cofactor-phospholipid complex. Anti-Beta 2 Glycoprotein 1 antibodies have been shown to be more specific for thrombosis than anticardiolipin antibodies in patients with antiphopholipid syndrome. An ELISA assay is utilized to detect antibodies directed against Beta-2 Glycoprotien 1 in the patient's serum. |
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Methodology
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ELISA |
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Performed
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Wednesday |
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Turnaround Time
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1-5 days |
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Specimen Requirements
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5 mL serum (red top or SST tube)
Separate from cells as soon as possible and freeze immediately.
Transport frozen.
Minimum volume 2 mL.
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Rejection Criteria
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Serum hemolyzed, icteric, or lipemic. |
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CPT Code(s)
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86146 x 3 |
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Reference Range
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IgG ≤ 8 GPS
IgM ≤ 14 MPS
IgA ≤ 18 APS
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Contact Information
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Hemostasis Lab: 214-645-5067
Customer Service: 214-645-7057, Toll Free 877-887-8136 |
Last Modified: March 12, 2008 |
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