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| Test Description |
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Test Name
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Chromosome Analysis, Blood, Constitutional (non-leukemic study) |
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Synonym(s)
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Cytogenetics, Blood, Constitutional
Karyotype, Blood, Constitutional
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Description
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Analysis of chromosomes in peripheral blood for the diagnosis of constitutional (congenital) chromosome aberrations. |
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Methodology
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72-hour culture with phytohemagglutinin, standard cytogenetic harvest, G-banded with trypsin-Wright stain. The chromosomes in twenty metaphase spreads are counted, five cells are fully analyzed, and two karyotypes are prepared. |
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Performed
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Daily. |
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Turnaround Time
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8 - 10 days. Preliminary results can be provided earlier if necessary. |
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Specimen Requirements
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Minimum 3 mL aseptically collected blood in a 5 ml green top, sodium heparin tube (or 2 ml pediatric green top, sodium heparin tube). DO NOT use lithium heparin tubes.
Note: Deliver to lab at room temperature within 24 hours. If collected over a weekend, call the laboratory to make arrangements for specimen delivery. May be refrigerated if not transported immediately. Do not freeze. Protect from heat or cold
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Rejection Criteria
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Frozen, clotted, hemolyzed or grossly contaminated specimens. Incorrect anticoagulant used. |
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CPT Code(s)
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88230, 88262, 88291 |
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Reference Range
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See interpretive report. |
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Contact
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Cytogenetics Lab: (214) 645-7000
Customer Service: (214) 645-7057 or Toll Free (877) 887-8136 |
Last Modified: May 5, 2008 |
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