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Class 1: 1998-2002
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Kevin H. Gardner, Ph.D.
W.W. Caruth Jr. Scholar in Biomedical Research
Associate Professor, Departments of Biochemistry and Pharmacology
Dr. Gardner seeks to elucidate the molecular basis of the sensory and regulatory mechanisms used by the PAS (Per-Arnt-Sim) family of protein/protein interaction domains by combining biophysical, biochemical, and chemical approaches in the study of kinases and transcription factors.
Lab Web Site
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Jin Jiang, Ph.D.
Eugene McDermott Scholar in Medical Research
Associate Professor, Center for Developmental Biology and
Department of Pharmacology
Dr. Jiang is carrying out systematic genetic screens to identify genes controlling cell growth and patterning. His research focuses on genes of the Hh and Wnt pathways that have been linked to many types of human cancers.
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Makoto Kuro-O, M.D., Ph.D.
Southwestern Medical Foundation Scholar in Biomedical Research
Assistant Professor, Department of Pathology
Dr. Kuro-O's research is focused on understanding the molecular basis of aging with a focus on the gene, termed klotho, which is involved in the suppression of aging in mammals. He uses the klotho mouse, a mouse homozygous for a disruption of the klotho locus (kl/kl), as an animal model to study this potential “anti-aging"hormone.
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Hongtao Yu, Ph.D.
Michael L. Rosenberg Scholar in Medical Research
Associate Professor, Department of Pharmacology
Dr. Yu studies the molecular mechanisms governing chromosome inheritance and genetic integrity using a multidisciplinary approach. His work focuses on how the mitotic spindle checkpoint proteins form an intracellular signaling network to prevent premature separation of sister chromatids during mitosis of mammalian cells.
Lab Web Site
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