Research Interests:

• Genetics of quantitative traits

Recent Publications:

1. Jonathan C. Cohen, Ph.D., Eric Boerwinkle, Ph.D., Thomas H. Mosley, Jr., Ph.D., and Helen H. Hobbs, M.D. (2006) Sequence Variations in PCSK9, Low LDL, and Protection against Coronary Heart Disease. New England Journal of Medicine 354:1310-1312.
2. Langheim S, Yu L, von Bergmann K, Lutjohann D, Xu F, Hobbs HH, Cohen JC., "ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile." J Lipid Res., 46(8):1732-8, August 2005 
3. Moschetta A, Xu F, Hagey LR, van Berge Henegouwen GP, van Erpecum KJ, Brouwers JF, Cohen JC, Bierman M, Hobbs HH, Steinbach JH, Hofmann AF., "A phylogenetic survey of biliary lipids in vertebrates." J Lipid Res., August 2005
4. Yu L, von Bergmann K, Lutjohann D, Hobbs HH, Cohen JC., "Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8." J Lipid Res., 46(8):1739-44, August 2005
5. Weng L, Kavaslar N, Ustaszewska A, Doelle H, Schackwitz W, Hebert S, Cohen JC, McPherson R, Pennacchio LA., "Lack of MEF2A mutations in coronary artery disease." J Clin Invest., 115(4):1016-10, April 2005
6. Guerra R, Yu Z, Marcovina S, Peshock R, Cohen JC, Hobbs HH., "Lipoprotein(a) and apolipoprotein(a) isoforms: no association with coronary artery calcification in the Dallas Heart Study." Circulation., 111(12):1471-9, March 2005

For additional publications: Search PubMed

Education:

• University of Cape Town, South Africa, B.S., Physiology, 1983
• University of Cape Town, South Africa, B.S. Hons, First Class, 1984
• University of Cape Town, South Africa, Ph.D., Physiology, 1989
• UT Southwestern Medical Center, Center for Human Nutrition, Postdoctoral Fellow, 1989-1990
• UT Southwestern Medical Center, Department of Molecular Genetics, Postdoctoral Fellow, 1990-1992

Professional Positions:

• 2000-Present - Associate Professor of Internal Medicine, UT Southwestern Medical Center
• 1994-2000 - Assistant Professor of Internal Medicine, UT Southwestern Medical Center
• 1992-1994 - Assistant Professor, Center for Human Nutrition,  UT Southwestern Medical Center
• 1991-1992 - Instructor, Center for Human Nutrition, UT Southwestern Medical Center