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Department of Pediatrics: Allergy & Immunology Research
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The allergy and immunology division focused on basic research in drug hypersensitivity for many years.  While we continue to address clinically relevant drug allergy questions, the major research focus of the division has shifted to pediatric asthma.  We recently completed a very important NIH-funded multicenter study that examined the relationship between indoor allergens and asthma-associated morbidity in inner city children. 

Currently, the division is participating in two additional pediatric inner city studies.  The aim of the first study, which is entitled, " Community Leadership in Preventing Asthma - CLIP Asthma", is to determine whether allergens in school environment contribute to asthma-associated morbidity.  Another aim of the study is to determine better methods for asthma screening in schools.  The second study a NIH-funded multi-center study that will be evaluating whether a biomarker-supplemented approach to asthma therapy improves asthma outcomes as compared to a guidelines-based approach without the use of a specific biomarker.  The biomarker to be evaluated in this protocol will be exhaled nitric oxide. 

The Division of Allergy and Immunology has ongoing clinical research in adult and pediatric asthma and allergy.  The following is a list of current research activities:                     
        

Research Name

 UT Southwestern IRB #

Community Leadership in Preventing Asthma (CLIP)

 0103-033

Characterization of Langerhans Cells in Atopic Dermatitis

 0402-193

Prevention of Rhinitis Medicamentosa with Intranasal Steroids

 0502-272

Primary Care Clinic Intervention Involving Asthma Management 

 0400-197

ImmunoCAP Results of Hospitalized Asthmatic Children

 0703-443

Retrospective Analysis of Patients with Steven Johnson Syndrome or Toxic Epidermal Necrolysis at a Tertiary Burn Center

 0803-496

Adverse Reaction to Medications Cross-Reactive with Sulphonamides in Patients with Reported Adverse Reaction to Sulphonamides

 0803-514

Celphalosporin Administration to Patients with Histories of Penicillin Allergies

 0903-582