The Center for Cancer and Blood Disorders (CCBD) is the clinical site for Pediatric Hematology-Oncology care at UT Southwestern. The CCBD is based at Children's Medical Center Dallas.  The CCBD is one of the largest pediatric hematology-oncology programs in the United States and is internationally known as a center of excellence in patient care, education, clinical and laboratory research, and patient advocacy.

• The Center for Cancer and Blood Disorders (CCBD) at Children's handles over 12,000 outpatient visits (8,500 oncology, 3,500 hematology) and 1,300 admissions per year. Patients are treated in a new 22-bed inpatient hematology-oncology unit at Children's.
• More than 200 new cases of childhood cancer and 500 children with hematological disorders are diagnosed annually.
• Clinical Programs include:
  - Oncology
  - Stem Cell Transplantation
  - Childhood Cancer Survivor Program
  - General Hematology
  - Sickle Cell Disease
  - Hemophilia
  - Comprehensive Orthopedic Oncology
  - Neuro-Oncology

Parkland Memorial Hospital, a 997-bed county hospital, handles more than 15,000 newborn deliveries each year and is the site of the newborn nursery. The pediatric hematology-oncology staff provides a consult service for newborn patients with hematological conditions. Children's and Parkland are both contiguous with The University of Texas Southwestern Medical Center at Dallas.

A multidisciplinary approach is used in the CCBD to plan and deliver clinical care that is targeted to meet the needs of each child.  Among the services offered are child life, social work, child psychiatry, nutritional support, pastoral care, physical and occupational therapy and prosthetics services. Currently there are four oncology clinical nurse practitioners who care for patients on the inpatient and outpatient services, three sickle cell disease clinical nurse practitioners and one clinical nurse practitioner devoted to the care of hemophilia patients. The outpatient clinics are fully staffed by clinic nurses and all the clinic days have defined doctor nurse teams to care for patients seen on different days.