Name: Wanpen Vongpatanasin, M.D.
Academic Title: Associate Professor
Primary Appointment: Internal Medicine
Secondary Appointment: Internal Medicine - Hypertension and Cardiology
Professional Overview
Education:
M.D. 1990 Chulalongkorn University
Residency:
1991 - 1994 UT Southwestern Internal Mediciine
Fellowships:
1994 - 1998 UT Southwestern Cardiology
Board Certifications:
American Board of Internal Medicine
Cardiovascular disease
Hypertension Specialist
Professional Associations / Affiliations:
American Heart Association
American College of Cardiology
American College of Physician
American Society of Hypertension
American Physiological Society
Laboratory Interest:
Dr. Vongpatanasin's research interest is in the area of neural control of blood pressure and the influence of various hormones and antihypertensive agents on the autonomic control of blood pressure in humans. Her laboratory has performed autonomic studies in both normal healthy subjects and patients with hypertension or autonomic dysfunction. Clinical trial: Diuretic treatment for high blood pressure
Personnel:
Zhongyun Wang, M.D. - Postdoctoral Research Fellow
Debbie A. Arbique, R.N. - Research Nurse
Publications in the past 5 years:
1. Szczepaniak LS, Dobbins RL, Metzger GJ, Sartoni-D’Ambrosia G, Arbique D, Vongpatanasin W, Unger R, Victor RG. Myocardial Triglycerides and Systolic Function in Humans: in vivo Evaluation by Localized Proton Spectroscopy and Cardiac Imaging. Magn Reson Med 2003;49:417–423.
2. Barman S, Fadel PJ, Vongpatanasin W, Victor RG. Gebber G. Basis for the Cardiac-Related Rhythm in Muscle Sympathetic Nerve Activity of Humans. Am J Physiol 2003;284:H584-97.
3. Vongpatanasin W, Tuncel M, Wang Z, Arbique D, Mehrad B, Jialal I. Differential Effects of Oral vs. Transdermal estrogen Replacement Therapy on C-reactive Protein in Postmenopausal Women. J Am Coll Cardiol 2003;41:1358-63.
4. Fadel PJ, Wang Z, Tuncel M, Watanabe H, Abbas A, Arbique D, Vongpatanasin W, Haley RW, Victor RG, Thomas GD. Metaboreflex activation of muscle sympathetic nerve discharge during static exercise is severely impaired with myophosphorylase deficiency. J Physiol 2003;548: 983-993.
5. Vongpatanasin W, Taylor JA, Victor RG. Effects of cocaine on heart rate variability in healthy subject. Am J Cardiol 2004;93:385-8.
6. Fadel PJ, Barman S, Vongpatanasin W, Victor RG. Gebber G. Fractal Properties of Human Muscle Sympathetic Nerve Activity. Am J Physiol 2004;286:H1076-H1087.
7. Haley RW, Vongpatanasin W, Wolfe GI, Bryan WW, Armitage R, Hoffmann RF, Callahan TS, Charuvastra E, Shell WE, Marshall WW, Victor RG. Blunted Circadian Variation in Autonomic Regulation of Sinus Node Function in Veterans with Gulf War Syndrome. Am J Med 2004 2004;117:469–478.
8. Abbas A, Fadel P, Wang Z, Arbique D, Abbas A, Jialal I, Vongpatanasin W. Contrasting Effects of Oral vs. Transdermal estrogen Replacement Therapy on Serum Amyloid A (SAA) and HDL-SAA in Postmenopausal Women. Art Throm Vasc Biol 2004;24:e164-7.
9. Fadel PJ, Wang Z, Watanabe H, Arbique D, Vongpatanasin W, Thomas GD. Augmented sympathetic vasoconstriction in exercising forearms of postmenopausal women is reversed by oestrogen therapy. J Physiol. 2004 561:893-901.
10. Khera A, McGuire DK, Murphy SA, Stanek HG, Das SR, Vongpatanasin W, Wians FH Jr, Grundy SM, de Lemos JA. Race and gender differences in C-reactive protein levels. J Am Coll Cardiol. 2005;46:464-9.
11. Menon DV, Vongpatanasin W. Effects of transdermal estrogen replacement therapy on cardiovascular risk factors. Treat Endocrinol. 2006;5:37-51.
12. Seetharam D, Mineo C, Gormley AK, Gibson LL, Vongpatanasin W, Chambliss KL, Hahner LD, Cummings ML, Kitchens RL, Marcel YL, Rader DJ, Shaul PW. High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I . Circ Res. 2006;98:63-72.
13. Li JL, Canham RM, Vongpatanasin W, Leonard D, Auchus, RJ, Victor, RG. Do Allelic Variants in alpha 2A and alpha 2C Adrenergic Receptors Predispose to Hypertension in Blacks? Hypertension. 2006 47:1140-6.
14. Nwariaku FE, Miller BS, Auchus R, Holt S, Watumull L, Dolmatch B, Nesbitt S, Vongpatanasin W, Victor R, Wians F, Livingston E, Snyder WH 3rd. Primary hyperaldosteronism: effect of adrenal vein sampling on surgical outcome. Arch Surg. 2006;141:497-503.
15. Ashraf M, Vongpatanasin W. Estrogen and Hypertension. Current Hypertension Reports 2006;8:368-76
16. Vongpatanasin W, Thomas GD, Schwartz R, Cassis LA, Osborne-Lawrence S, Hahner L, Gibson LL, Black S, Samols D, and Shaul PW. CRP Causes Downregulation of Vascular AT2 Receptors and Systolic Hypertension in Mice. Circulation 2007;115(8):1020-8.
17. Schwartz R, Osborne-Lawrence S, Hahner L, Gibson LL, Gormley AK, Vongpatanasin W, Zhu W, Word RA, Seetharam D, Black S, Samols D, Mineo C, Shaul PW. C-reactive Protein Downregulates Endothelial NO Synthase and Attenuates Reendothelialization In Vivo in Mice. Circ Res 2007;100(10):1452-9.
18. Auchus RJ, Chandler DW, Singeetham S, Chokshi N, Nwariaku FE, Dolmatch BL, Holt SA, Wians Jr FH, Josephs SC, Trimmer CK, Lopera J, Vongpatanasin W, Nesbitt SD, Leonard D, Victor RG. Differential Diagnosis of Primary Aldosteronism Based on Adrenal Vein 18-Hydroxycorticosterone Concentrations. J Clin Endo 2007 ;92(7):2648-51.
19. Menon DV, Wang Z, Fadel PJ, Arbique D, Leonard D, Li J-L, Victor RG, Vongpatanasin W. Central Sympatholysis as a Novel Countermeasure for Cocaine-Induced Sympathetic Activation and Vasoconstriction in Humans. J Am Coll Cardiol 2007;50:626–33.
20. Vongpatanasin W. Cardiovascular morbidity and mortality in high-risk populations: epidemiology and opportunities for risk reduction. J Clin Hypertens (Greenwich). 2007;9:11-5.
