| Ad Title: |
Do you have Macular Degeneration (wet)? |
| Study Title: |
A Randomized, Double Masked, Active Controlled Phase III Study of the Efficacy, Safety and Tolerability of Repeated Doses of Intravitreal VEGF Trap-Eye in Subjects with Neovascular Age-Related Macular Degeneration |
| Protocol Number: |
062008-040 |
| Department(s) involved in the Study: |
Ophthalmology
|
| Purpose of the Study: |
Assess the effectiveness of intravitreal (ITV) administered VEGF(Vascular Endothelial Growth Factor) Trap-Eye compared to ranibizumab (Lucentis) in preventing moderate vision loss in patients with neovascular (wet) AMD. The primary endpoint of this study is to prevent vision loss of greater than or equal to 15 letters on the Early Treatment Diabetic Retinopathy Study (ETDRS) chart when compared to baseline at 52 weeks. |
| Participant Eligibility: |
Major Inclusion:
Participants 50 years of age and older.
Evidence of Macular Degeneration as specified by the study protocol and confirmed by study doctor.
Major Exclusions:
Any prior ocular (in the study eye) or systemic treatment or surgery for neovascular (wet) AMD except dietary supplements or vitamins. |
| Disease/Condition Under Study: |
Neovascular Age Related Macular Degeneration (wet) |
| Cancer Related Study: |
No
|
| Study Drug(s): |
VEGF Trap-Eye
|
| Study Device(s): |
|
| Study Doctor: |
Dr. Yuguang He |
| Location of Study: |
|
Sites
|
Recruiting at this Site
|
|
Aston Ambulatory Care Center
|
Yes
|
|
| Contact Phone: |
214-645-2014 |
| Email: |
Jessica.Janecek-Griffin@UTSouthwestern.edu |
| Other Information: |
|
| Website Keywords: |
Ophthalmology
|
| Medical Keywords: |
Macular Degeneration, Night Blindness, Ocular, Wet Macular Degeneration
|
