| Ad Title: |
Experienced heart attack in the recent past- 6 days back? |
| Study Title: |
A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome (ACS) Subjects with Unstable Angina/Mon-ST-Elevation Myocardial Infarction (UA/NSTEMI) Who are Medically Manager - The TRILOGY ACS Study |
| Protocol Number: |
052008-052 |
| Department(s) involved in the Study: |
Cardiology, Emergency Medicine, General Internal Medicine, Int Med - Cardiology, Int Med - General Medicine, Internal Medicine
|
| Purpose of the Study: |
To evaluate the efficacy and safety of antiplatelet drugs- Prasugrel and Clopidogrel in UA/NSTEMI Acute Coronary Syndrome (ACS) patients who are medically managed. |
| Participant Eligibility: |
1.Have had a UA/NSTEMI index event within 7 days (168 hours) prior to randomization.
2.Have had a medical management strategy decision made with reasonable certainty; that is, neither PCI nor CABG is planned for treatment of the index event.
3.Have had at least 1 of the following 3 high-risk features at the time of the UA/NSTEMI event:
a) Age -60 years(or) greater.
b) Prior MI evidenced by pre-existing Q waves,or demonstration of infarction on imaging studies, or prior documentation of elevated cardiac markers.
c) Diabetes Mellitus - defined by concomitant treatment with an oral hypoglycemic agent and/or insulin.
4.Have at least 1 native coronary artery stenosis >50% (applies only to those subjects who undergo diagnostic coronary angiography within 7 days of the onset of the index event but do not undergo PCI or CABG after angiography is performed).
|
| Disease/Condition Under Study: |
Acute Coronary Syndrome- UA (Unstable Angina)(or) NSTEMI (Non- ST segment Elevated Myocardial Infarction). |
| Cancer Related Study: |
No
|
| Study Drug(s): |
bayer (aspirin), effient (prasugrel), plavix (clopidogrel)
|
| Study Device(s): |
|
| Study Doctor: |
Dr. Darren McGuire |
| Location of Study: |
|
Sites
|
Recruiting at this Site
|
|
Parkland Memorial Hospital
|
Yes
|
|
UT Southwestern University Hospitals St. Paul Building
|
Yes
|
|
Aston Ambulatory Care Center
|
Yes
|
|
UT Southwestern Medical Center
|
Yes
|
|
| Contact Phone: |
214-648-9384 |
| Email: |
Joju Joy@utsouthwestern.edu |
| Other Information: |
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| Website Keywords: |
Cardiac Electrophysiology, Cardiology, Cardiothoracic Surgery, Emergency Medicine, Vascular
|
| Medical Keywords: |
Acute Cadiac Syndrome (ACS), Cardiac Research, Cardiology, Cardiololgy research, General Internal Medicine, Heart attack, Internal Medicine, Internal Medicine- Cardiology, Myocardial Infarction- MI, Non ST Segment Elevation Myocardial Infarction , NSTEMI, Unstable Angina (UA)
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