| Ad Title: |
Diuretic treatment for high blood pressure |
| Study Title: |
Neural Mechanisms of Thiazide Diuretics-Induced Insulin Resistance |
| Protocol Number: |
022004-016 |
| Department(s) involved in the Study: |
Int Med - Cardiology, Internal Medicine
|
| Purpose of the Study: |
To determine if currently approved medication treatment for high blood pressure have different effects on the nerve activity which controls blood pressure and blood sugar levels |
| Participant Eligibility: |
Men and women between 18-65 with high blood pressure between 140-149/90-99 mmHg.Study excludes subjects with heart diseases, diabetes mellitus, lung disease, cancer, and thyroid problems. |
| Disease/Condition Under Study: |
Hypertension, high blood pressure, insulin resistance
|
| Cancer Related Study: |
No
|
| Study Drug(s): |
chlorthalidone, clonidine hydrochloride, eplerenone, insulin, irbesartan, phenylephrine hydrochloride, quinapril, Sodium nitroprusside, spironolactone
|
| Study Device(s): |
|
| Study Doctor: |
Dr. Wanpen Vongpatanasin |
| Location of Study: |
|
Sites
|
Recruiting at this Site
|
|
General Clinical Research Center
|
Yes
|
|
| Contact Phone: |
214_648_2968 |
| Email: |
Debbie.Arbique@Utsouthwestern.Edu |
| Other Information: |
Medications will be provided free of charge. Participants will be compensated for their time. |
| Website Keywords: |
Vascular
|
| Medical Keywords: |
diuretics, high blood pressure, hypertension, insulin resistance
|
