| Ad Title: |
Cervical Cancer |
| Study Title: |
A Phase II, Open-Label, Randomized, Multicenter Trial of Pazopanib (GW786034) in Combination with Lapatinib (GW572016) Compared to Pazopanib Monotherapy and Lapatinib Monotherapy in Subjects with FIGO Stage IVB or Recurrent or Persistent Cervical Cancer with Zero or One Prior Chemotherapy Regimen for Adanced/Recurrent Disease (VEG105281) |
| Protocol Number: |
102006-047 |
| Department(s) involved in the Study: |
Obstetrics & Gynecology, Simmons Comprehensive Cancer Center
|
| Purpose of the Study: |
To see if Pazopanib and Lapatinib used together are more effective in treating recurrent or persistent cervical cancer than using each drug alone. |
| Participant Eligibility: |
Must have Stage IVB or Recurrent or Persistent Cervical Cancer.
Must have had zero or one prior chemotherapy regimen for advanced disease.
|
| Disease/Condition Under Study: |
Persistent or recurrent cervical cancer |
| Cancer Related Study: |
Yes
|
| Study Drug(s): |
GW572016 (Lopatinib), GW786034 (Pazopanib)
|
| Study Device(s): |
|
| Study Doctor: |
Dr. Jayanthi Lea |
| Location of Study: |
|
Sites
|
Recruiting at this Site
|
|
Parkland Memorial Hospital
|
Yes
|
|
UT Southwestern University Hospitals St. Paul Building
|
Yes
|
|
UT Southwestern University Hospitals Zale Lipshy Building
|
Yes
|
|
Aston Ambulatory Care Center
|
Yes
|
|
UT Southwestern Medical Center
|
Yes
|
|
| Contact Phone: |
214_648_1854 |
| Email: |
Jayanthi.Lea@Utsouthwestern.Edu |
| Other Information: |
This trial is sponsored by GlaxooSmithKline. |
| Website Keywords: |
Gyn Oncology
|
| Medical Keywords: |
cancer, cervical cancer
|
