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Clinical Trials :: Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST)



Ad Title: Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST)
Study Title: Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST)
Protocol Number: 062005-055
Department(s) involved in the Study: Neurology, Surgery
Purpose of the Study: To determine the safest way to prevent strokes in people who have a partial blockage (or narrowing) of the carotid artery. For this purpose the study will compare the results of carotid Endarterectomy (open surgery) vs. carotid stenting
Participant Eligibility: Adult men and women who have moderate to severe narrowing of at least one of their carotid arteries.
Disease/Condition Under Study: Carotid artery stenosis
Cancer Related Study: No
Study Drug(s):
Study Device(s): Carotid stent system (Acculink/RX Acculink)
Study Doctor: Dr. Carlos Timaran
Location of Study:
Sites Recruiting at this Site
Parkland Memorial Hospital Yes
UT Southwestern University Hospitals St. Paul Building Yes
Dallas Veteran's Affairs Medical Center Yes
Contact Phone: 214_645_0553
Email: Eric.Rosero@UTsouthwestern.edu
Other Information: CREST is a study for people who have narrowing in their carodit artery, with or without symptoms such as small strokes or temporary strokes called transient ischemic attacks (TIA). This research study will compare carotid endarterectomy, a common operation to prevent stroke, to a procedure called carotid artery stenting, where a metal device called a stent is placed in the narrowed part of the carotid artery to hold it open. Patients who agree to participate in the CREST study will receive either carotid endarterectomy OR carotid artery stenting. For additional information about the study please visit our website at www.CRESTtrial.org
Website Keywords: Stroke, Surgery, Vascular
Medical Keywords: Atherosclerosis, carotid