| Ad Title: |
Diabetic Nephropathy |
| Study Title: |
Improving Outcomes in Diabetic Nephropathy |
| Protocol Number: |
0202-065 |
| Department(s) involved in the Study: |
Int Med - Nephrology
|
| Purpose of the Study: |
The purpose of this research is to determine if adding on a medication to standard care prevents your kidney disease from getting worse. This study is being done because diabetes is the number one cause of kidney failure. |
| Participant Eligibility: |
1. Adult men and women ages 20-65.
2. Type I Diabetes: Start of diabetes needing insulin before age 25 and having for at least 5 years.
3. Type II Diabetes: Start of diabetes at 20 years of age and older and being treated with oral hypoglycemic medication and/or insulin.
4. Systolic blood pressure > 130 mmHg.
5. Proteinuria in a 24 hr. urine sample while on ACE inhibitor (example: lisinopril).
6. On an ACE inhibitor or ARB medication for at least 3 months (example: lisinopril or losartan). |
| Disease/Condition Under Study: |
Diabetic Nephropathy |
| Cancer Related Study: |
No
|
| Study Drug(s): |
Losartan, spironolactone
|
| Study Device(s): |
|
| Study Doctor: |
Dr. Robert Toto |
| Location of Study: |
|
Sites
|
Recruiting at this Site
|
|
Parkland Memorial Hospital
|
Yes
|
|
Aston Ambulatory Care Center
|
Yes
|
|
General Clinical Research Center
|
Yes
|
|
| Contact Phone: |
214-648-7847 |
| Email: |
suzan.morrison@utsouthwestern.edu |
| Other Information: |
This is a 12 month study for the treatment of proteinuria in Type 1 and Type 2 Diabetics. The medications being used for this study are all FDA approved. All patients will receive lisinopril and the "study" medication which will either be losartan, spironolactone or a placebo.
All of the study medications, clinic visits and lab tests are at no cost to the patients. |
| Website Keywords: |
Diabetes, Nephrology
|
| Medical Keywords: |
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