Dr. Huang’s research interest is to use magnetic resonance imaging (MRI), especially diffusion tensor imaging (DTI) technology, to study the structures of brain and apply the structural information to answer various types of biological questions. For clinical studies, physical parameters and tractography derived from DTI are used to quantitatively characterize abnormality of brains with neurological and psychiatric diseases. High resolution is pushed for animal imaging at high magnetic field to obtain both macro- and micro- structural information which can be used to detect morphological difference of animals with pathological models.
RESEARCH INTERESTS
Diffusion tensor magnetic resonance imaging (DT-MRI)
Animal MRI
DTI based tractography
Pulse sequence development
RECENT PUBLICATIONS
H. Huang, A. Yamamoto, M.A. Hossain, L. Younes, S. Mori, "Quantitative cortical mapping of fractional anisotropy of developing rat brains" Journal of Neuroscience, Vol. 28, No. 6:1427-1433, 2008
H. Huang, C. Ceritoglu, X. Li, A. Qiu, M.I. Miller, P.C.M. van Zijl, S. Mori, "Correction of B0 susceptibility induced distortion in diffusion-weighted images using large-deformation diffeomorphic metric mapping" Magnetic Resonance Imaging, 26:1294-1302, 2008
SIGNIFICANT PUBLICATIONS
H. Huang, J. Zhang, S. Wakana, W. Zhang, T. Ren, L.J. Richards, P. Yarowsky, P. Donohue, E. Graham, P. van Zijl, S. Mori, "White and Gray Matter Development in Human Fetal, Newborn and Pediatric Brains" NeuroImage, Vol. 33, No. 1:27-38, 2006
H. Huang, J. Zhang, H. Jiang, S. Wakana, L. Poetscher, M.I. Miller, PCM van Zijl, A.E. Hillis, R. Wytik, S. Mori, "DTI Tractography based Parcellation of White Matter: Application to the Mid-sagittal Morphology of Corpus Callosum" NeuroImage, Vol. 26, No. 1:195-205, 2005
H. Huang, J. Zhang, P.C.M. van Zijl, S. Mori, "Analysis of Noise Effects on DTI-based Tractography Using the Brute-Force and Multi-ROI Approach" Magnetic Resonance in Medicine, Vol. 52:559-565, 2004
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