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Steven Altschuler

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Steven Altschuler, Ph.D.

Details of Research

Name:		Steven Altschuler, Ph.D.
Academic Title:		Associate Professor
Primary Appointment:		Pharmacology
School:		Southwestern Medical School
Degree Program:		Cell Regulation Molecular Biophysics
Non-degree Program:		STARS SURF
Affiliations:		Green Center for Systems Biology Simmons Comprehensive Cancer Center
Lab Website:		Altschuler and Wu Laboratory
Email:		Steven Altschuler, Ph.D.

RESEARCH INTERESTS

	Systems biology
	Cancer
	Cell polarity

RECENT PUBLICATIONS

	Altschuler SJ, Angenent SB, Wang Y, Wu LF, "On the spontaneous emergence of polarity" Nature, 454:886-890, August 2008
	Weiner, O.D., Marganski, W.A., Wu, L.F., Altschuler, S.J., Krischner, M.W., "An actin-based wave generator organizes cell motility" PLOS Biology, 5:221, August 2007
	Loo, L.H., Wu, L., Altschuler, S.J., "Image-based multivariate profiling of drug responses from single cells" Nature Methods, 4:445, May 2007
	Marco, E., Wedlich-Soldner, R., Li, R., Altschuler, S.J., Wu, L.F., "Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity" Cell, 129:411, April 2007
	Maciag, K., Altschuler, S.J., Slack, M.D., Krogan, N.J., Emili, A., Greenblatt, J.F., Maniatis, T., Wu, L.F., "Systems-level analyses identify extensive coupling among gene expression machines" Molecular Systems Biology, 2:1, January 2006

SIGNIFICANT PUBLICATIONS

	Altschuler SJ, Angenent SB, Wang Y, Wu LF, "On the spontaneous emergence of polarity" Nature, 454:886-890, August 2008
	Loo, L.H., Wu, L., Altschuler, S.J., "Image-based multivariate profiling of drug responses from single cells" Nature Methods, 4:445, May 2007
	Marco, E., Wedlich-Soldner, R., Li, R., Altschuler, S.J., Wu, L.F., "Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity" Cell, 129:411, April 2007
	Perlman, Z.E., Slack, M.D., Feng, Y., Mitchison, T.J., Wu, L.F., Altschuler, S.J., "Multi-dimensional drug profiling by automated microscopy." Science, 306(5699):1194-1198, 2004
	Wedlich-Soldner, R., Altschuler, S.J., Wu, L.F., Li, R., "Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase." Science, 299(5610):1231-1235, 2003

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