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Jinming Gao

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Jinming Gao, Ph.D.

Details of Research

Name:		Jinming Gao, Ph.D.
Academic Title:		Associate Professor
Primary Appointment:		Simmons Comprehensive Cancer Center
Secondary Appointment:		Pharmacology
School:		Southwestern Medical School
Degree Program:		Genetics and Development
Affiliations:		The Harold C. Simmons Comprehensive Cancer Center
Department Website:		Simmons Comprehensive Cancer Center
Lab Website:		Jinming Gao Lab Website
Email:		Jinming Gao, Ph.D.

RESEARCH OVERVIEW

	The Gao Lab combines research expertise in materials science, molecular imaging and cancer biology to establish integrated nanomedicine platforms for early detection and intervention of cancer. The underlying theme of our research is to translate key advances in materials science and nanotechnology into better clinical diagnosis and therapy of cancer.

RESEARCH INTERESTS

	Cancer nanomedicine
	Targeted drug delivery
	Cancer molecular imaging
	Polymer biomaterials
	MRI molecular probes

RECENT PUBLICATIONS

	Blanco E, Bey EA, Dong Y, Weinberg BD, Sutton DM, Boothman DA, Gao J, "Beta-Lapachone-containing PEG-PLA Polymer Micelles as Novel Nanotherapeutics against NQO1-overexpressing Tumor Cells" Journal of Controlled Release, Epub Spring 2007
	Sutton D, Nasongkla N, Blanco E, Gao J., "Functionalized Micellar Systems for Cancer Targeted Drug Delivery" Pharm. Res., 24:1029-1046, Fall 2007
	Bey, E.A.; Bentle, M.S.; Reinicke, K.E.; Dong, Y.; Yang, C.R.; Girard, L.; Minna, J.D.; Bornmann, W.G.; Gao, J.; Boothman, D.A., "A Novel NQO1- and PARP-1-Mediated Cell Death Pathway Induced In Non-Small Cell Lung Cancer Cells By beta-Lapachone" Proc. Natl. Acad. Sci. USA, 104:11832-11837, 2007
	Sumer, B.; Gao, J., "Theranostic Nanomedicine for Cancer" Nanomedicine, 3:137, 2008
	Barcena, C.; Sra, A.K.; Chaubey, G.S.; Khemtong, C.; Liu, J.P.; Gao, J., "Zinc Ferrite Nanoparticles as MRI Contrast Agents" Chem.Comm., 2224-2226, 2008

SIGNIFICANT PUBLICATIONS

	Gao, J.; Mammen, M.; Whitesides, G. M., "Evaluating Electrostatic Contributions to Binding with the Use of Protein Charge Ladders" Science, 272/5261:535-537, 1996
	Niklason, L.; Gao, J.; Abbott, W.; Hirschi, K.; Houser, S.; Marini, R.; Langer, R., "Functional Arteries Grown in Vitro" Science, 5413/284:489-493, 1999
	Nasongkla N, Bey EA, Ren J, Ai H, Khemtong C, Setti JG, Chin SF, Sherry AD, Boothman DA, Gao J, "Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems" Nano Letters, 6:2427-2430, Fall 2006
	Ai, H.; Flask, C.; Weinberg, R.; Shuai, X.; Pagel, M.; Farrell, D.; Duerk, J.; Gao, J., "Magnetite-Loaded Polymeric Micelles as Novel Magnetic Resonance Probes" Adv. Mater., 17:1949-1952, 2003
	Nasongkla, N.; Shuai, X.; Ai, H.; Weinberg, B.D.; Pink, J.; Boothman, D.A.; Gao, J., "cRGD-Functionalized Polymer Micelles for Targeted Doxorubicin Delivery" Angew. Chem. Int. Ed., 43/46:6323-6327, 2004

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