My primary research interest is male osteoporosis and male hypogonadism/andropause. 25% of 1.5 million total fractures happen in men every year. In first year after hip fracture mortality is above 30% in men and more then half do not reach they previous activity level. Yet we know much less about epidemiology, etiology and treatment modalities of male osteoporosis as compared with women. I am currently testing different treatment options for male osteoporosis. Male Hypogonadism/Andropause (low testosterone level with associated symptoms) is closely related to osteoporosis. It is more common in older men and can cause decreased energy, decreased bone strength and muscle mass, increased fat mass and decreased sexual function. I am currently studying testosterone replacement in men on dialysis.
RESEARCH INTERESTS
Male osteoporosis
Hypogonadism
RECENT PUBLICATIONS
Gruntmanis U, Braunstein GD, "Treatment of Gynecomastia" Current Opinion in Investigational Drugs, 2:643-649, 2001
Welch LB, Denke AM, Kermani A, Adams-Huet B, Gazmen MN, and Gruntmanis U., "Comparison of Testosterone, Biphosphonate and Combination of both therapies in men with low Bone Mineral Density" Journal of Investigative Medicine, 55(4):168-73, August 2007
Gruntmanis U, Leach B, Odvina CV, Zerwekh JE, Sakhaee K, "High Rate of Hypogonadism and Vitamin D Insufficiency in Males on Dialysis." J Bone Miner Res, 2005; 20 (suppl 1): M46 September 2005
Gruntmanis U, "Male Osteoporosis: Deadly but Ignored" American Journal of Medical Sciences, 333 (2):85-92, February 2007
Ghayee KH, Kalyanova P, Patel V and Gruntmanis U, "No Difference in Prevalence of Pituitary Imaging Abnormalities in Men with Secondary Hypogonadism presenting with Decreased Bone Mineral Density versus Erectile Dysfunction" Endocrinologist In press,
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