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Udit Verma

 
 
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Udit Verma, M.D.

 Details of Research

Biographical Sketch Details of Research Personal Overview How to Contact
Udit Verma
Name:
  Udit Verma, M.D.
Academic Title:
  Assistant Professor
Primary Appointment:
  Internal Medicine - Hematology-Oncology
School:
  Southwestern Medical School
Affiliations:
  Seay Biomedical Building
The Harold C. Simmons Comprehensive Cancer Center
Physician Profile:
  Udit Verma, M.D.

 RESEARCH INTERESTS
 
NF-kappaB Pathway
Exploring Role of siRNA Cancer Therapy
Molecular Targets of Cancer Chemotherapy
 
 RECENT PUBLICATIONS
 
Kwak YT, Li R, Becerra C, Tripathy D, Frenkel E, Verma UN, "Ikappa B kinase alpha (IKKalpha ) regulates sub-cellular distribution and turnover of cyclin D1 by phosphorylation" J Biol Chem, 280:33945-52, September 2005
Verma UN, Becerra C, "The Varied Applications of Small Interference RNA" Progress in Clinical Oncology, 2004:1-24, 2005
Guo J, Verma UN, Gaynor RB, Frenkel EP, Beccera CR, "Enhanced Chemosensitivity to Irinotecan by RNA interference mediated down-regulation of the NF-B p65 subunit" Clin Cancer Res, 10:3333, 2004
Verma UN, Yamamoto Y, Prajapati and Gaynor RB, "Nuclear Role of I kappa B Kinase-gamma/NF-kappa B essential modulator (IKK gamma/NEMO) in NF-kappa B-dependent gene expression" J Biol Chem, 279:3509, 2004
Prajapati, S., Verma, UN., Yamamoto, Y., Kwak, Y. T., and Gaynor, R. B, "Protein phosphatase 2Cβ association with the IκB kinase complex is involved in regulating NF-κB activity" J Biol Chem, 279:1739, 2004
 
 SIGNIFICANT PUBLICATIONS
 
Yamamoto Y, Verma UN, Prajapati S, and Gaynor RB, "A nucleosomal role of IKKalpha in histone H3 phosphorylation is critical for cytokine-induced activation of NF-kB regulated genes" Nature, 423:655, 2003
Berman, K., Verma, UN, Harburg, G., "Sulindac enhances TNF-a mediated lung cancer cell apoptosis by inhibition of NF-kB." Clinical Cancer Research, 8:354-60, February 2002
Verma, UN, Surabhi, RM, Schmaltieg, A., Becerra, C and Gaynor, R. B., "Small interfering RNAs directed against B-catenin inhibit the in vitro and in vivo growth of colon cancer cells." Clinical Cancer Research, 9:1291-300, April 2003
Verma, UN, Bagg, A., Brown, E., Mazumder, A., "Interleukin-2 activation of human bone marrow in long term cultures: an effective strategy for purging and generation of anti-tumor cytotoxic effectors." Bone Marrow Transplant, 13:115, 1994
Verma UN, Misra R, Radhakrisnan S, Maitra SC, Agarwal S, Singh RR, "A syndrome of fibrosing pleuritis, pericarditis and synovitis with infantile contracture of fingers and toes in two sisters: Familial fibrosing serositis" J Rheumatology, 22:2349, 1995
 
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