Molecular basis of the development and neoplastic progression of Barrett’s esophagus
RESEARCH INTERESTS
Barrett's esophagus
Molecular mechanisms of gastrointestinal cancer
Esophageal adenocarcinoma
RECENT PUBLICATIONS
Hormi-Carver K, Feagins LA, Spechler SJ, Souza RF., "All trans-retinoic acid (ATRA) induces apoptosis via p38 and caspase pathways in metaplastic Barrett?s cells." American Journal of Physiology, 290:G335-G342, 2006
Feagins LA, Zhang H, Hormi-Carver K, Quinones MH, Thomas D, Zhang X, Terada LS, Spechler SJ, Ramirez RD, Souza RF, "Acid has anti-proliferative effects in non-neoplastic Barrett?s epithelial cells." American Journal of Gastroenterology, 102:10-20, 2007
Jaiswal KR, Morales CP, Feagins LA, Gandia KG, Zhang X, Zhang HY, Hormi-Carver, K, Shen Y, Elder F, Ramirez RD, Sarosi GA, Jr., Spechler SJ, Souza RF., "Characterization of a telomerase-immortalized, non-neoplastic, human Barrett’s cell line (BAR-T)." Diseases of the Esophagus, 20:256-264, 2007
Souza RF, Lunsford T, Ramirez RD, Zhang X, Lee EL, Shen Y, Owen C, Shay JW, Morales CM, Spechler SJ., "GERD is associated with short telomeres in the squamous epithelium of the distal esophagus." American Journal of Physiology, 293:G19-G24, 2007
Zhang HY, Zhang X, Hormi-Carver K, Feagins LA, Spechler SJ, Souza RF., "In non-dysplastic Barrett?s Epithelial (BAR-T) cells, acid exerts early anti-proliferative effects through activation of the Chk2 pathway." Cancer Research, In press 2007
Point and right click (click and hold for Mac users) your mouse onand select "Save this link (or target) as..." option to save the file to your local computer.
and select "Save this link (or target) as..." option to save the file to your local computer.