Engelking, L.J., Evers, B.M., Richardson, J.A., Goldstein, J.L., Brown, M.S. and Liang, G., "Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin" J. Clin. Invest., 116:2356-2365, September 2006
Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS., "Schoenheimer effect explained - feedback regulation of cholesterol synthesis in mice mediated by Insig proteins" J Clin Invest, 115 (9):2489-2498, September 2005
Kuriyama H, Liang G, Engelking LJ, Horton JD, Goldstein JL, Brown MS., "Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver." Cell Metab, 1(1):41-51, January 2005
Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G., "Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis." J Clin Invest., 113(8):1168-75, April 2004
Daisuke Yabe, Ryutaro Komuro, Guosheng Liang, Joseph L Goldstein, and Michael S Brown, "Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis" Proc. Natl. Acad. Sci. USA, 100 (6):3155-3160, March 2003
SIGNIFICANT PUBLICATIONS
Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS., "Schoenheimer effect explained - feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." J Clin Invest., 115(9):2489-98, September 2005
Kuriyama H, Liang G, Engelking LJ, Horton JD, Goldstein JL, Brown MS., "Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver." Cell Metab., 1(1):41-51, January 2005
Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS., "Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c." J Biol Chem., 277(11):9520-8, March 2002
Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, Shimomura I, Shan B, Brown MS, Goldstein JL, Mangelsdorf DJ., "Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta." Genes Dev., 14(22):2819-30., November 2000
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