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Xin Zhou

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Xin Zhou, M.D.

Details of Research

Name:		Xin Jin Zhou, M.D.
Endowed Title:		Drs. George and Anne Race Distinguished Professorship of Pathology
Academic Title:		Professor
Primary Appointment:		Pathology
Secondary Appointment:		Internal Medicine
School:		Southwestern Medical School
Affiliations:		Pathology
Department Website:		Pathology
Lab Website:		Veripath Laboratories
Email:		Xin Zhou, M.D.

RESEARCH INTERESTS

	Cellular and Molecular Mechanisms of Hypertension and Renal Diseases
	Pathogenesis of lupus nephritis in murine models of SLE

RECENT PUBLICATIONS

	C. Xie, R. Patel, T. Wu, T. J. Zhu, Henry, M. Bhaskarabhatla, R. Samudrala, K. Tus, Y. Gong, H. Zhou, E. Wakeland, X.J. Zhou, C. Mohan (* Co-senior authors), "PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr." Int Immunol, 19:509-522, 2007
	X.J. Zhou, D. Rakheja, X.Q. Yu, N.D. Vaziri, F.G. Silva, "Tha aging kidney" Kidney International, 74:710-720, 2008
	J.H. Zhen, H. Lu, X.Q. Wang, N.D. Vaziri, X.J. Zhou, "Upregulation of endothelial nitric oxide synthase in human endothelial cells by reactive oxygen species." Am J Hypertens, 21:28-34, 2008
	X.J. Zhou, R. Saxena, Z.H. Liu, N.D. Vaziri, F.G. Silva, "Renal senescence in 2008: progress and chanllenges." Int Urol Nephrol, 40:823-839, 2008
	N.D. Vaziri, X.J. Zhou, "Potential mechanisms of adverse outcomes in trials of anemia correction in chronic kidney disease." Nephrol Dial Transpl, 24:1082-1088, 2009

SIGNIFICANT PUBLICATIONS

	X.J. Zhou, Z. Laszik, T. Nadasdy, V. D’Agati, F.G. Silva (eds), "Silva’s Diagnostic Renal Pathology" Cambridge University Press, New York, New York, 2009
	X.J. Zhou, F.G. Silva, "Membranoproliferative glomerulonephritis" Heptinstall’s Pathology of the Kidney, 6th edition, In Jennette JC, Olson JL, Schwartz MM, Silva FG (eds), 253-319, 2007
	S. Subramanian, K. Tus, Q. Li, A. Wang, X. Tian, J. Zhou, C. Liang, G. Bartov, L. McDaniel, X.J. Zhou, R. Schultz, E.K. Wakeland, "A Tlr translocation accelerates systemic autoimmunity in murine lupus." Proc Natl Aca Sci, USA, 103:9970-9975, 2006
	T. Wu, X. Qin, Z. Kurepa, K. Kumar, K. Liu, M. Bhaskarabhatla, X.J. Zhou, A. Satterthwaite, L. Davis, C. Mohan, "Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus" J Clin Invest, 117:2186-2196, 2007
	Z. Liang, C. Xie, C. Chen, D. Kreska, K. Hsu, L. Li, X.J. Zhou, C. Mohan, "Pathogenetic profiles and molecular signatures of antinuclear autoantibodies derived from NZM2410 lupus mice." J Exp Med, 199:381-398, 2004

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