Structure and function of mitochondrial multienzyme complexes
Heat shock and chaperone proteins
RECENT PUBLICATIONS
Machius, M., Chuang, J.L., Wynn, R.M., Tomchick, D.R, and Chuang, D.T., "Structure of rat BCKD kinase: nucleotide-induced domain communication in a mitochondrial protein kinase" Proc Natl Acad Sci U S A., 98(20):11218-23, September 2001
Chuang, J.L., Wynn, R.M., and Chuang, D.T., "The C-terminal hinge region of lipoic acid-bearing domain of E2b is essential for domain interaction with branched-chain alpha-keto acid dehydrogenase kinase" J Biol Chem, 277(40):36905-8., August 2002
Wynn, R.M., Chuang, J.L., Sansaricq, C., Mandel, H., and Chuang, D.T., "Biochemical basis of type IB (E1beta ) mutations in maple syrup urine disease. A prevalent allele in patients from the Druze kindred in Israel" J Biol Chem, 276(39):36550-6, July 2001
Wynn, R.M., Machius, M., Chuang, J.L., Li, J., Tomchick, D.R., and Chuang, D.T., "Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase" J. Biol Chem., Epublication August 2003
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