G Protein Signaling in Mammalian Development, Adult Physiology and Behavior
RECENT PUBLICATIONS
Huang J, Pashkov V, Kurrasch DM, Yu K, Gold SJ, & Wilkie TM., "Feeding and fasting controls liver expression of a Regulator of G protein Signaling (Rgs16) in periportal hepatocytes." Comparative Hepatology, 5:doi:10.1186/1476-5926-5-8, 2006
Wilkie TM & Kinch L., "New roles for Ga and RGS proteins: Communication continues despite driving sisters apart." Current Biology, 15:R843-R854, November 2005
Sierra DA, Gilbert DJ, Householder D, Grishin NV, Yu K, Ukidwe P, Barker S, He W, Wensel TG, Otero G, Brown G, Copeland NG, Jenkins NA & Wilkie TM, "Evolution of the regulators of G protein signaling (RGS) multigene family in mouse and human." Genomics, 79:177-185, 2002
Ivey K, Tyson B, Ukidwe P, McFadden D, Levi G, Olson E, Srivastava D & Wilkie TM, "G alpha-q and Galpha-11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme." Developmental Biology, 255:230-237, 2003
Luo X, Popov S, Bera AK, Wilkie TM & Muallem S, "Regulators of G protein signaling provide biochemical control of agonist-evoked [Ca2+]i oscillations." Molecular Cell, 7:651-660, 2001
SIGNIFICANT PUBLICATIONS
Ross EM & Wilkie TM, "GTPase-activating proteins (GAPs) for heterotrimeric G proteins: Regulators of G protein signaling (RGS proteins) and their relatives." Annual Review of Biochemistry, 69:795-827, 2000
Popov S, Krishna UM, Falck JR & Wilkie TM, "Ca2+/calmodulin reverses 3,4,5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity." J. Biol. Chem., 275:18962-18968, 2000
Zeng W, Xu X, Popov S, Mukhopadhyay S, Chidiac P, Swistok J, Danho W, Yagaloff K, Fisher S, Ross EM, Muallem S & Wilkie TM, "The N-terminal domain of RGS4 confers receptor selective inhibition of G protein signaling" J. Biol. Chem., 273:34687-34690, 1998
Popov S, Yu K, Kozasa T & Wilkie TM, "The RGS domains of RGS4, RGS10 and GAIP retain GAP activity in vitro." Proc. Natl. Acad Sci. USA, 94:7216-7220, 1997
Berman DM, Wilkie TM & Gilman AG, "GAIP and RGS4 are GTPase accelerating proteins (GAPs) for the Gi family of heterotrimeric guanine nucleotide binding proteins." Cell, 86:445-452, 1996
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