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Stephen Turley

 
 
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Stephen Turley, Ph.D.

 Details of Research

Biographical Sketch Details of Research Personal Overview How to Contact
Stephen Turley
Name:
  Stephen Dean Turley, Ph.D.
Academic Title:
  Professor
Primary Appointment:
  Internal Medicine - Digestive and Liver Diseases
Department Website:
  Division of Digestive and Liver Diseases
Email:
  Stephen Turley, Ph.D.

 RESEARCH INTERESTS
 
cholesterol metabolism
sterol absorption
bile acid metabolism
gallstone disease
heart disease
 
 RECENT PUBLICATIONS
 
Repa, J.J., Turley, S.D., Quan, G. and Dietschy, J.M., "Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption" J. Lipid Res., 46:779-789, 2005
Garver, W.S., Xie, C., Repa, J.J., Turley, S.D., Dietschy, J,M., "Niemann-Pick C1 expression is not regulated by the amount of cholesterol flowing through cells in the mouse" J. Lipid Res., 46:1745-1754, 2005
Beltroy, E.P., Richardson, J.A., Horton, J.D., Turley, S.D., Dietschy, J.M., "Cholesterol accumulation and liver cell death in the mouse with Niemann-Pick type C disease" Hepatology, 42:886-893, 2005
Beltroy, E.P., Liu, B., Dietschy, J.M., Turley, S.D., "Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease" J Lipid Res, 48:869-881, Summer 2007
Turley, S.D., "Role of Niemann-Pick C1-like 1 (NPC1L1) in intestinal sterol absorption" J Clin Lipidol, 2:S20-S28, March 2008
 
 SIGNIFICANT PUBLICATIONS
 
Turley, S.D. and Dietschy, J.M., "The contribution of newly synthesized cholesterol to biliary cholesterol in the rat" J. Biol. Chem., 256:2438-2446, 1981
Turley, S.D., Burns, D.K., Rosenfeld, C.R. and Dietschy, J.M., "Brain does not utilize low density lipoprotein-cholesterol during fetal and neonatal development in the sheep" J. Lipid Res., 37:1953-1961, 1996
Turley, S.D., Spady, D.K. and Dietschy, J.M., "Identification of a metabolic difference accounting for the hyper- and hyporesponder phenotypes of cynomolgus monkey" J. Lipid Res., 38:1598-1611, 1997
Repa, J.J., Lund, E.G., Horton, J.D., Leitersdorf, E., Russell, D.W., Dietschy, J.D. and Turley, S.D., "Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia: reversal by cholic acid feeding" J. Biol. Chem., 275:39685-39692, 2000
Liu, B., Li H., Repa, J.J., Turley, S.D., Dietschy, J.M., "Genetic variations and treatments that affect the lifespan of the NPC1 mouse" J Lipid Res, 49:663-669, Winter 2008
 
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