The Bipolar Disorder Research Program at UT Southwestern is a nationally recognized specialty program focusing on patients with disorders within the bipolar spectrum, including patients diagnosed with schizoaffective disorder, bipolar type, and cyclothymia. Dr. Suppes’ research interests include long-term treatment strategies for bipolar disorder, treatment strategies for bipolar II disorder, use of treatment algorithms, and combination treatment strategies for the bipolar spectrum.
RESEARCH INTERESTS
Bipolar Disorder
Pharmacology
RECENT PUBLICATIONS
Suppes T, Dennehy EB, "Evidence-Based Long-Term Treatment of Bipolar II Disorder" Journal of Clinical Psychiatry, 63 (suppl 10):29-33, Winter 2002
Altshuler LL, Suppes T, Black DO, Nolen WA, Leverich G, Keck PE, Jr., Frye MA, Kupka R, McElroy SL, Grunze H, Kitchen CM, Post R., "Lower switch rate in depressed patients with bipolar II than bipolar I disorder treated adjunctively with second-generation antidepressants" American Journal of Psychiatry, 163(2):313-315, 2006
Suppes T, Mintz J, McElroy SL, Altshuler LL, Kupka RW, Frye MA, Keck PE, Nolen WA, Leverich GS, Grunze H, Rush AJ, Post RM, "Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Bipolar Treatment Network: A sex-specific phenomenon" Archives of General Psychiatry, 62(10):1089-1096, 2005
Suppes T, Dennehy EB, Hirschfeld RMA, Altshuler LL, Bowden CL, Calabrese JR, Crismon ML, Ketter TA, Sachs G, Swann AC for the Texas Consensus Conference Panel on Medication Treatment of Bipolar Disorder, "The Texas Implementation of Medication Algorithms: Update to the algorithms for treatment of bipolar I disorder" Journal of Clinical Psychiatry, 66(7):870-886, 2005
Leverich GS, Altshuler LL, Frye MA, Suppes T, McElroy SL, Keck PE, Jr., Kupka RW, Denicoff KD, Nolen WA, Grunze H, Martinez MI, Post RM, "Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers" American Journal of Psychiatry, 163(2):232-239, 2006
SIGNIFICANT PUBLICATIONS
Suppes T, Baldessarini RJ, Faedda GL, Tohen M, "Risk of recurrence following discontinuation of lithium treatment in bipolar disorder" Arch Gen Psychiatry, 48:1082-1088, 1991
Suppes T, Webb A, Paul B, Carmody T, Kraemer H, Rush AJ, "Clinical outcome in a randomized one-year trial of clozapine versus treatment as usual for patients with treatment-resistant illness and a history of mania" Am J Psychiatry, 156:1164-1169, 1999
Suppes, T, Rush JA, Dennehy EB, Crismon LM, Kashner MT, Toprac MG, Carmody TJ, Brown SE, Biggs MM, Shores-Wilson K, Witte B, Trivedi M, Miller AL, Altshuler KZ, Shon SP, "Texas Medication Algorithm Project (TMAP): Clinical Results for Patients with a History of Mania" J Clin Psychiatry, 64(4):370-382, 2003
Suppes T, Mintz J, McElroy SL, Altshuler LL, Kupka RW, Frye MA, Keck PE, Nolen WA, Leverich GS, Grunze H, Rush AJ, Post RM, "Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Bipolar Treatment Network: A sex-specific phenomenon" Archives of General Psychiatry, 62(10):1089-1096, 2005
Suppes T, Dennehy EB, Hirschfeld RMA, Altshuler LL, Bowden CL, Calabrese JR, Crismon ML, Ketter TA, Sachs G, Swann AC for the Texas Consensus Conference Panel on Medication Treatment of Bipolar Disorder, "The Texas Implementation of Medication Algorithms: Update to the algorithms for treatment of bipolar I disorder" Journal of Clinical Psychiatry, 66(7):870-886, 2005
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