His research has focused on the development and testing of innovative treatments for mood disorders including medication combinations, psychotherapy, and somatic treatments, as well as disease management protocols (treatment algorithms) for depression and bipolar disorder.
RESEARCH INTERESTS
Mood disorders
Psychopharmacology
Psychotherapy
Treatment resistant depressions
Treatment selection
RECENT PUBLICATIONS
M. Fava, A.J. Rush, S. Wisniewski, et al., "A comparison of mirtazapine and nortriptyline following two consecutive failed medication treatments for depressed outpatients: A STAR*D report." American Journal of Psychiatry, 163(7):1161-1172, 2006
A.J. Rush, M. Trivedi, S. Wisniewski, et al., "Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report." American Journal of Psychiatry, 163:1905-1917, 2006
SIGNIFICANT PUBLICATIONS
A.J. Rush, A.T. Beck, M. Kovacs, et al., "Comparative efficacy of cognitive therapy and pharmacotherapy in the treatment of depressed outpatients." Cognitive Therapy and Research, 1:17-37, 1977
A.J. Rush, M.K. Erman, M.A. Schlesser, et al., "Alprazolam versus amitriptyline in depressions with reduced REM latencies." Archives of General Psychiatry, 42:1154-1159, 1985
A. J. Rush, M.L. Crismon, T.M. Kashner, et al., "Texas Medication Algorithm Project, Phase 3: Rationale and study design." Journal of Clinical Psychiatry, 64:357-369, 2003
A.J. Rush, M. Fava, S. Wisniewski, et al., "Sequenced Treatment Alternatives to Relieve Depression (STAR*D): Rationale and design." Controlled Clinical Trials, 25(1):119-142, 2004
M.H. Trivedi, A.J. Rush, M.L. Crismon, et al., "Clinical results for patients with major depressive disorder in the Texas Medication Algorithm Project (TMAP)." Archives of General Psychiatry, 61(7):669-680, 2004
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